About Large ribosomal subunit protein mL66
Large ribosomal subunit protein mL66 (MRPS18A) is a protein
from Homo sapiens identified by UniProt accession
Q9NVS2, 196 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein mL66 |
|---|
| UniProt accession | Q9NVS2 |
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| Gene | MRPS18A |
|---|
| Organism | Homo sapiens |
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| Length | 196 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (23)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.47
- neutrophil count · score 0.17
- leukocyte count · score 0.17
- myeloid white cell count · score 0.15
- platelet count · score 0.05
- blood protein measurement · score 0.03
- hemoglobin measurement · score 0.03
- hematocrit · score 0.03
- monocyte count · score 0.02
- vascular endothelial growth factor measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NVS2-F1 | alphafold | PREDICTED | 85.67 | — |
Amino-acid sequence (196 residues)
MAALKALVSG CGRLLRGLLA GPAATSWSRL PARGFREVVE TQEGKTTIIE GRITATPKES PNPPNPSGQC PICRWNLKHK YNYDDVLLLS QFIRPHGGML PRKITGLCQE EHRKIEECVK MAHRAGLLPN HRPRLPEGVV PKSKPQLNRY LTRWAPGSVK PIYKKGPRWN RVRMPVGSPL LRDNVCYSRT PWKLYH
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