About Transmembrane protein 51
Transmembrane protein 51 (TMEM51) is a protein
from Homo sapiens identified by UniProt accession
Q9NW97, 253 residues long.
MolForge cross-references it against 0 known binders and
39 disease associations.
Target properties
| Protein name | Transmembrane protein 51 |
|---|
| UniProt accession | Q9NW97 |
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| Gene | TMEM51 |
|---|
| Organism | Homo sapiens |
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| Length | 253 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (39)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- serum urea measurement · score 0.23
- adolescent idiopathic scoliosis · score 0.21
- migraine disorder · score 0.14
- Headache · score 0.12
- Familial exudative vitreoretinopathy · score 0.05
- erythrocyte count · score 0.05
- type 2 diabetes mellitus · score 0.05
- systemic lupus erythematosus · score 0.05
- Ischemic stroke · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NW97-F1 | alphafold | PREDICTED | 60.02 | — |
Amino-acid sequence (253 residues)
MMAQSKANGS HYALTAIGLG MLVLGVIMAM WNLVPGFSAA EKPTAQGSNK TEVGGGILKS KTFSVAYVLV GAGVMLLLLS ICLSIRDKRK QRQGEDLAHV QHPTGAGPHA QEEDSQEEEE EDEEAASRYY VPSYEEVMNT NYSEARGEEQ NPRLSISLPS YESLTGLDET TPTSTRADVE ASPGNPPDRQ NSKLAKRLKP LKVRRIKSEK LHLKDFRINL PDKNVPPPSI EPLTPPPQYD EVQEKAPDTR PPD
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