Mediator of RNA polymerase II transcription subunit…

About Mediator of RNA polymerase II transcription subunit 9

Mediator of RNA polymerase II transcription subunit 9 (MED9) is a protein from Homo sapiens identified by UniProt accession Q9NWA0, 146 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Mediator of RNA polymerase II transcription subunit 9
UniProt accession	Q9NWA0
Gene	MED9
Organism	Homo sapiens
Length	146 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.51
glucose measurement · score 0.24
birth weight · score 0.23
triglyceride measurement · score 0.20
chronotype measurement · score 0.19
protein measurement · score 0.16
body height · score 0.16
HbA1c measurement · score 0.13
lean body mass · score 0.12
testosterone measurement · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NWA0-F1	alphafold	PREDICTED	75.42	—

Amino-acid sequence (146 residues)

MASAGVAAGR QAEDVLPPTS DQPLPDTKPL PPPQPPPVPA PQPQQSPAPR PQSPARAREE ENYSFLPLVH NIIKCMDKDS PEVHQDLNAL KSKFQEMRKL ISTMPGIHLS PEQQQQQLQS LREQVRTKNE LLQKYKSLCM FEIPKE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Mediator of RNA polymerase II transcription subunit 9 (MED9)