About Protein BEX4
Protein BEX4 (BEX4) is a protein
from Homo sapiens identified by UniProt accession
Q9NWD9, 120 residues long.
MolForge cross-references it against 0 known binders and
83 disease associations.
Target properties
| Protein name | Protein BEX4 |
|---|
| UniProt accession | Q9NWD9 |
|---|
| Gene | BEX4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 120 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (83)
Diseases linked to this target (Open Targets).
- oral squamous cell carcinoma · score 0.08
- glioblastoma multiforme · score 0.08
- Blackfan-Diamond anemia · score 0.06
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.05
- hemoglobin D disease · score 0.05
- neoplasm · score 0.05
- Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 · score 0.05
- alpha thalassemia-intellectual disability syndrome type 1 · score 0.05
- delta-beta-thalassemia · score 0.05
- dominant beta-thalassemia · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NWD9-F1 | alphafold | PREDICTED | 63.33 | — |
Amino-acid sequence (120 residues)
MESKEELAAN NLNGENAQQE NEGGEQAPTQ NEEESRHLGG GEGQKPGGNI RRGRVRRLVP NFRWAIPNRH IEHNEARDDV ERFVGQMMEI KRKTREQQMR HYMRFQTPEP DNHYDFCLIP
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