About Solute carrier family 52, riboflavin transporter, member 1
Solute carrier family 52, riboflavin transporter, member 1 (SLC52A1) is a protein
from Homo sapiens identified by UniProt accession
Q9NWF4, 448 residues long.
MolForge cross-references it against 0 known binders and
34 disease associations.
Target properties
| Protein name | Solute carrier family 52, riboflavin transporter, member 1 |
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| UniProt accession | Q9NWF4 |
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| Gene | SLC52A1 |
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| Organism | Homo sapiens |
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| Length | 448 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (34)
Diseases linked to this target (Open Targets).
- ariboflavinosis · score 0.42
- maternal riboflavin deficiency · score 0.42
- body height · score 0.23
- late-onset Alzheimers disease · score 0.13
- keratoconus · score 0.11
- mean platelet volume · score 0.08
- creatinine measurement · score 0.06
- infection · score 0.05
- infect · score 0.05
- intraocular pressure measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NWF4-F1 | alphafold | PREDICTED | 83.77 | — |
Amino-acid sequence (448 residues)
MAAPTLGRLV LTHLLVALFG MGSWAAVNGI WVELPVVVKD LPEGWSLPSY LSVVVALGNL GLLVVTLWRQ LAPGKGEQVP IQVVQVLSVV GTALLAPLWH HVAPVAGQLH SVAFLTLALV LAMACCTSNV TFLPFLSHLP PPFLRSFFLG QGLSALLPCV LALVQGVGRL ECPPAPTNGT SGPPLDFPER FPASTFFWAL TALLVTSAAA FRGLLLLLPS LPSVTTGGSG PELQLGSPGA EEEEKEEEEA LPLQEPPSQA AGTIPGPDPE AHQLFSAHGA FLLGLMAFTS AVTNGVLPSV QSFSCLPYGR LAYHLAVVLG SAANPLACFL AMGVLCRSLA GLVGLSLLGM LFGAYLMALA ILSPCPPLVG TTAGVVLVVL SWVLCLCVFS YVKVAASSLL HGGGRPALLA AGVAIQVGSL LGAGAMFPPT SIYHVFQSRK DCVDPCGP
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