Transmembrane protein 242 (TMEM242)

About Transmembrane protein 242

Transmembrane protein 242 (TMEM242) is a protein from Homo sapiens identified by UniProt accession Q9NWH2, 141 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	Transmembrane protein 242
UniProt accession	Q9NWH2
Gene	TMEM242
Organism	Homo sapiens
Length	141 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.47
smoking status measurement · score 0.36
risk-taking behaviour · score 0.26
lipoprotein A measurement · score 0.16
heel bone mineral density · score 0.06
gut microbiome measurement · score 0.04
mean platelet volume · score 0.04
Red cell distribution width · score 0.04
post-traumatic stress disorder · score 0.04
drug use measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NWH2-F1	alphafold	PREDICTED	72.17	—

Amino-acid sequence (141 residues)

METAGAATGQ PASGLEAPGS TNDRLFLVKG GIFLGTVAAA GMLAGFITTL SLAKKKSPEW FNKGSMATAA LPESGSSLAL RALGWGSLYA WCGVGVISFA VWKALGVHSM NDFRSKMQSI FPTIPKNSES AVEWEETLKS K

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards