About Spermine oxidase
Spermine oxidase (SMOX) is a protein
from Homo sapiens identified by UniProt accession
Q9NWM0, 555 residues long.
MolForge cross-references it against 0 known binders and
176 disease associations.
Target properties
| Protein name | Spermine oxidase |
|---|
| UniProt accession | Q9NWM0 |
|---|
| Gene | SMOX |
|---|
| Organism | Homo sapiens |
|---|
| Length | 555 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (176)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.53
- reticulocyte measurement · score 0.52
- body height · score 0.50
- mean corpuscular hemoglobin concentration · score 0.48
- Immature Reticulocyte Fraction Measurement · score 0.48
- mean corpuscular hemoglobin · score 0.47
- leukocyte count · score 0.45
- Red cell distribution width · score 0.43
- lymphocyte count · score 0.42
- mean corpuscular volume · score 0.40
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NWM0-F1 | alphafold | PREDICTED | 87.30 | — |
Amino-acid sequence (555 residues)
MQSCESSGDS ADDPLSRGLR RRGQPRVVVI GAGLAGLAAA KALLEQGFTD VTVLEASSHI GGRVQSVKLG HATFELGATW IHGSHGNPIY HLAEANGLLE ETTDGERSVG RISLYSKNGV ACYLTNHGRR IPKDVVEEFS DLYNEVYNLT QEFFRHDKPV NAESQNSVGV FTREEVRNRI RNDPDDPEAT KRLKLAMIQQ YLKVESCESS SHSMDEVSLS AFGEWTEIPG AHHIIPSGFM RVVELLAEGI PAHVIQLGKP VRCIHWDQAS ARPRGPEIEP RGEGDHNHDT GEGGQGGEEP RGGRWDEDEQ WSVVVECEDC ELIPADHVIV TVSLGVLKRQ YTSFFRPGLP TEKVAAIHRL GIGTTDKIFL EFEEPFWGPE CNSLQFVWED EAESHTLTYP PELWYRKICG FDVLYPPERY GHVLSGWICG EEALVMEKCD DEAVAEICTE MLRQFTGNPN IPKPRRILRS AWGSNPYFRG SYSYTQVGSS GADVEKLAKP LPYTESSKTA PMQVLFSGEA THRKYYSTTH GALLSGQREA ARLIEMYRDL FQQGT
Explore Spermine oxidase with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets