About PCNA-interacting partner
PCNA-interacting partner (PARPBP) is a protein
from Homo sapiens identified by UniProt accession
Q9NWS1, 579 residues long.
MolForge cross-references it against 0 known binders and
90 disease associations.
Target properties
| Protein name | PCNA-interacting partner |
|---|
| UniProt accession | Q9NWS1 |
|---|
| Gene | PARPBP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 579 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (90)
Diseases linked to this target (Open Targets).
- body height · score 0.39
- IGF-1 measurement · score 0.37
- neurodegenerative disease · score 0.37
- cortical thickness · score 0.30
- appendicular lean mass · score 0.29
- body weight · score 0.27
- risk-taking behaviour · score 0.26
- risky sexual behaviour measurement · score 0.22
- attention deficit hyperactivity disorder · score 0.20
- antisocial behaviour measurement · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NWS1-F1 | alphafold | PREDICTED | 70.42 | — |
Amino-acid sequence (579 residues)
MAVFNQKSVS DMIKEFRKNW RALCNSERTT LCGADSMLLA LQLSMAENNK QHSGEFTVSL SDVLLTWKYL LHEKLNLPVE NMDVTDHYED VRKIYDDFLK NSNMLDLIDV YQKCRALTSN CENYNTVSPS QLLDFLSGKQ YAVGDETDLS IPTSPTSKYN RDNEKVQLLA RKIIFSYLNL LVNSKNDLAV AYILNIPDRG LGREAFTDLK HAAREKQMSI FLVATSFIRT IELGGKGYAP PPSDPLRTHV KGLSNFINFI DKLDEILGEI PNPSIAGGQI LSVIKMQLIK GQNSRDPFCK AIEEVAQDLD LRIKNIINSQ EGVVALSTTD ISPARPKSHA INHGTAYCGR DTVKALLVLL DEEAANAPTK NKAELLYDEE NTIHHHGTSI LTLFRSPTQV NNSIKPLRER ICVSMQEKKI KMKQTLIRSQ FACTYKDDYM ISKDNWNNVN LASKPLCVLY MENDLSEGVN PSVGRSTIGT SFGNVHLDRS KNEKVSRKST SQTGNKSSKR KQVDLDGENI LCDNRNEPPQ HKNAKIPKKS NDSQNRLYGK LAKVAKSNKC TAKDKLISGQ AKLTQFFRL
Explore PCNA-interacting partner with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets