About Uncharacterized protein C2orf42
Uncharacterized protein C2orf42 (C2orf42) is a protein
from Homo sapiens identified by UniProt accession
Q9NWW7, 574 residues long.
MolForge cross-references it against 0 known binders and
35 disease associations.
Target properties
| Protein name | Uncharacterized protein C2orf42 |
| UniProt accession | Q9NWW7 |
| Gene | C2orf42 |
| Organism | Homo sapiens |
| Length | 574 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.41
- neutrophil count · score 0.31
- mean corpuscular volume · score 0.28
- leukocyte count · score 0.27
- myeloid white cell count · score 0.26
- red blood cell density measurement · score 0.24
- IGF-1 measurement · score 0.20
- mean reticulocyte volume · score 0.18
- erythrocyte count · score 0.18
- testosterone measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q9NWW7-F1 | alphafold | PREDICTED | 73.61 | — |
Amino-acid sequence (574 residues)
MEPNSLRTKV PAFLSDLGKA TLRGIRKCPR CGTYNGTRGL SCKNKTCGTI FRYGARKQPS VEAVKIITGS DLQVYSVRQR DRGPDYRCFV ELGVSETTIQ TVDGTIITQL SSGRCYVPSC LKAATQGVVE NQCQHIKLAV NCQAEATPLT LKSSVLNAMQ ASPETKQTIW QLATEPTGPL VQRITKNILV VKCKASQKHS LGYLHTSFVQ KVSGKSLPER RFFCSCQTLK SHKSNASKDE TAQRCIHFFA CICAFASDET LAQEFSDFLN FDSSGLKEII VPQLGCHSES TVSACESTAS KSKKRRKDEV SGAQMNSSLL PQDAVSSNLR KSGLKKPVVA SSLKRQACGQ LLDEAQVTLS FQDWLASVTE RIHQTMHYQF DGKPEPLVFH IPQSFFDALQ QRISIGSAKK RLPNSTTAFV RKDALPLGTF SKYTWHITNI LQVKQILDTP EMPLEITRSF IQNRDGTYEL FKCPKVEVES IAETYGRIEK QPVLRPLELK TFLKVGNTSP DQKEPTPFII EWIPDILPQS KIGELRIKFE YGHHRNGHVA EYQDQRPPLD QPLELAPLTT ITFP
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