tRNA selenocysteine 1-associated protein 1 (TRNAU1AP)

About tRNA selenocysteine 1-associated protein 1

tRNA selenocysteine 1-associated protein 1 (TRNAU1AP) is a protein from Homo sapiens identified by UniProt accession Q9NX07, 287 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein name	tRNA selenocysteine 1-associated protein 1
UniProt accession	Q9NX07
Gene	TRNAU1AP
Organism	Homo sapiens
Length	287 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (12)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.46
alcohol drinking · score 0.21
pulse pressure measurement · score 0.04
systolic blood pressure · score 0.03
hemoglobin measurement · score 0.03
brain measurement · score 0.03
self reported educational attainment · score 0.02
axial length measurement · score 0.01
psoriasis · score 0.01
nail-patella syndrome · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NX07-F1	alphafold	PREDICTED	75.65	—

Amino-acid sequence (287 residues)

MAASLWMGDL EPYMDENFIS RAFATMGETV MSVKIIRNRL TGIPAGYCFV EFADLATAEK CLHKINGKPL PGATPAKRFK LNYATYGKQP DNSPEYSLFV GDLTPDVDDG MLYEFFVKVY PSCRGGKVVL DQTGVSKGYG FVKFTDELEQ KRALTECQGA VGLGSKPVRL SVAIPKASRV KPVEYSQMYS YSYNQYYQQY QNYYAQWGYD QNTGSYSYSY PQYGYTQSTM QTYEEVGDDA LEDPMPQLDV TEANKEFMEQ SEELYDALMD CHWQPLDTVS SEIPAMM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards