About Glucose-fructose oxidoreductase domain-containing protein 1
Glucose-fructose oxidoreductase domain-containing protein 1 (GFOD1) is a protein
from Homo sapiens identified by UniProt accession
Q9NXC2, 390 residues long.
MolForge cross-references it against 0 known binders and
32 disease associations.
Target properties
| Protein name | Glucose-fructose oxidoreductase domain-containing protein 1 |
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| UniProt accession | Q9NXC2 |
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| Gene | GFOD1 |
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| Organism | Homo sapiens |
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| Length | 390 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (32)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.35
- aspartate aminotransferase measurement · score 0.35
- hemoglobin measurement · score 0.35
- reticulocyte measurement · score 0.34
- neurofibrillary tangles measurement · score 0.31
- lymphocyte percentage of leukocytes · score 0.31
- reticulocyte count · score 0.30
- hematocrit · score 0.30
- neutrophil percentage of leukocytes · score 0.29
- red blood cell density measurement · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NXC2-F1 | alphafold | PREDICTED | 92.71 | — |
Amino-acid sequence (390 residues)
MLPGVGVFGT SLTARVIIPL LKDEGFAVKA LWGRTQEEAE ELAKEMSVPF YTSRIDEVLL HQDVDLVCIN LPPPLTRQIA VKTLGIGKNV ICDRTATPLD AFRMTSAAHY YPKLMSIMGN VLRFLPAFVR MKQLIEEGYV GEPLVCEVQV HGGSLLGKKY NWSCDDLMGG GGLHSVGTYI IDLLTFLTGQ KAVKVHGLLK TFVKQTDHIK GIRQITSDDF CTFQMVLEGG VCCTVTLNFN VPGEFKQDVT VVGSAGRLLA VGTDLYGQRN SAPEQELLVQ DATPVSNSLL PEKAFSDIPS PYLRGTIKMM QAVRQAFQDQ DDRRTWDGRP LTMAATFDDC LYALCVVDTI KRSSQTGEWQ NIAIMTEEPE LSPAYLISEA MRRSRMSLYC
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