About Zinc finger protein 586
Zinc finger protein 586 (ZNF586) is a protein
from Homo sapiens identified by UniProt accession
Q9NXT0, 402 residues long.
MolForge cross-references it against 0 known binders and
6 disease associations.
Target properties
| Protein name | Zinc finger protein 586 |
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| UniProt accession | Q9NXT0 |
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| Gene | ZNF586 |
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| Organism | Homo sapiens |
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| Length | 402 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (6)
Diseases linked to this target (Open Targets).
- allergic rhinitis · score 0.09
- sex hormone-binding globulin measurement · score 0.07
- mean corpuscular volume · score 0.04
- vitamin D measurement · score 0.02
- medulloblastoma · score 0.01
- glioblastoma multiforme · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NXT0-F1 | alphafold | PREDICTED | 73.34 | — |
Amino-acid sequence (402 residues)
MAAAAALRAP AQSSVTFEDV AVNFSLEEWS LLNEAQRCLY RDVMLETLTL ISSLGCWHGG EDEAAPSKQS TCIHIYKDQG GHSGERPYEC GEYRKLFKNK SCLTEPRRDH KHRNVRTGER PYECSKYGKL FHQKPTLHIH ERFHTGQKTY ECSECGKSFH QSSSLLQRQT LHTRERPYEC IECGKAFAEK SSLINHRKVH SGAKRYECNE CGKSFAYTSS LIKHRRIHTG ERPYECSECG RSFAENSSLI KHLRVHTGER PYECVECGKS FRRSSSLLQH QRVHTRERPY ECSECGKSFS LRSNLIHHQR VHTGERHECG QCGKSFSRKS SLIIHLRVHT GERPYECSDC GKSFAENSSL IKHLRVHTGE RPYECIDCGK SFRHSSSFRR HQRVHTGMRP YK
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