Actin-related protein 10 (ACTR10)

About Actin-related protein 10

Actin-related protein 10 (ACTR10) is a protein from Homo sapiens identified by UniProt accession Q9NZ32, 417 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein name	Actin-related protein 10
UniProt accession	Q9NZ32
Gene	ACTR10
Organism	Homo sapiens
Length	417 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (26)

Diseases linked to this target (Open Targets).

alcohol consumption measurement · score 0.16
smoking status measurement · score 0.12
Immature Reticulocyte Fraction Measurement · score 0.11
Red cell distribution width · score 0.09
mean platelet volume · score 0.08
mean corpuscular hemoglobin concentration · score 0.07
alcohol use disorder measurement · score 0.07
triglyceride measurement · score 0.07
BMI-adjusted waist-hip ratio · score 0.06
reticulocyte measurement · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NZ32-F1	alphafold	PREDICTED	83.30	—

Amino-acid sequence (417 residues)

MPLYEGLGSG GEKTAVVIDL GEAFTKCGFA GETGPRCIIP SVIKRAGMPK PVRVVQYNIN TEELYSYLKE FIHILYFRHL LVNPRDRRVV IIESVLCPSH FRETLTRVLF KYFEVPSVLL APSHLMALLT LGINSAMVLD CGYRESLVLP IYEGIPVLNC WGALPLGGKA LHKELETQLL EQCTVDTSVA KEQSLPSVMG SVPEGVLEDI KARTCFVSDL KRGLKIQAAK FNIDGNNERP SPPPNVDYPL DGEKILHILG SIRDSVVEIL FEQDNEEQSV ATLILDSLIQ CPIDTRKQLA ENLVVIGGTS MLPGFLHRLL AEIRYLVEKP KYKKALGTKT FRIHTPPAKA NCVAWLGGAI FGALQDILGS RSVSKEYYNQ TGRIPDWCSL NNPPLEMMFD VGKTQPPLMK RAFSTEK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards