About Splicing factor C9orf78
Splicing factor C9orf78 (C9orf78) is a protein
from Homo sapiens identified by UniProt accession
Q9NZ63, 289 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | Splicing factor C9orf78 |
|---|
| UniProt accession | Q9NZ63 |
|---|
| Gene | C9orf78 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 289 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (20)
Diseases linked to this target (Open Targets).
- hip bone mineral density · score 0.11
- hip bone size · score 0.11
- prostate carcinoma · score 0.10
- anemia · score 0.03
- cystatin C measurement · score 0.03
- neoplasm · score 0.02
- C-reactive protein measurement · score 0.02
- creatinine measurement · score 0.02
- protein measurement · score 0.02
- reticulocyte count · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NZ63-F1 | alphafold | PREDICTED | 68.74 | — |
Amino-acid sequence (289 residues)
MPVVRKIFRR RRGDSESEED EQDSEEVRLK LEETREVQNL RKRPNGVSAV ALLVGEKVQE ETTLVDDPFQ MKTGGMVDMK KLKERGKDKI SEEEDLHLGT SFSAETNRRD EDADMMKYIE TELKKRKGIV EHEEQKVKPK NAEDCLYELP ENIRVSSAKK TEEMLSNQML SGIPEVDLGI DAKIKNIIST EDAKARLLAE QQNKKKDSET SFVPTNMAVN YVQHNRFYHE ELNAPIRRNK EEPKARPLRV GDTEKPEPER SPPNRKRPAN EKATDDYHYE KFKKMNRRY
Explore Splicing factor C9orf78 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets