About Protein cornichon homolog 4
Protein cornichon homolog 4 (CNIH4) is a protein
from Homo sapiens identified by UniProt accession
Q9P003, 139 residues long.
MolForge cross-references it against 0 known binders and
126 disease associations.
Target properties
| Protein name | Protein cornichon homolog 4 |
|---|
| UniProt accession | Q9P003 |
|---|
| Gene | CNIH4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 139 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (126)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.30
- reticulocyte measurement · score 0.29
- reticulocyte count · score 0.29
- Red cell distribution width · score 0.29
- apolipoprotein A 1 measurement · score 0.26
- low density lipoprotein cholesterol measurement · score 0.26
- total cholesterol measurement · score 0.25
- leukocyte count · score 0.25
- appendicular lean mass · score 0.24
- neutrophil count · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P003-F1 | alphafold | PREDICTED | 92.93 | — |
Amino-acid sequence (139 residues)
MEAVVFVFSL LDCCALIFLS VYFIITLSDL ECDYINARSC CSKLNKWVIP ELIGHTIVTV LLLMSLHWFI FLLNLPVATW NIYRYIMVPS GNMGVFDPTE IHNRGQLKSH MKEAMIKLGF HLLCFFMYLY SMILALIND
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