Spliceosome-associated protein CWC15 homolog (CWC15)

About Spliceosome-associated protein CWC15 homolog

Spliceosome-associated protein CWC15 homolog (CWC15) is a protein from Homo sapiens identified by UniProt accession Q9P013, 229 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	Spliceosome-associated protein CWC15 homolog
UniProt accession	Q9P013
Gene	CWC15
Organism	Homo sapiens
Length	229 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.51
adolescent idiopathic scoliosis · score 0.11
electrocardiography · score 0.03
progesterone measurement · score 0.03
sex hormone-binding globulin measurement · score 0.02
infect · score 0.02
infection · score 0.02
systemic juvenile idiopathic arthritis · score 0.02
Abnormal sperm morphology · score 0.01
respiratory system disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9P013-F1	alphafold	PREDICTED	74.86	—

Amino-acid sequence (229 residues)

MTTAARPTFE PARGGRGKGE GDLSQLSKQY SSRDLPSHTK IKYRQTTQDA PEEVRNRDFR RELEERERAA AREKNRDRPT REHTTSSSVS KKPRLDQIPA ANLDADDPLT DEEDEDFEEE SDDDDTAALL AELEKIKKER AEEQARKEQE QKAEEERIRM ENILSGNPLL NLTGPSQPQA NFKVKRRWDD DVVFKNCAKG VDDQKKDKRF VNDTLRSEFH KKFMEKYIK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards