Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3)

About Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3

Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) is a protein from Homo sapiens identified by UniProt accession Q9P035, 362 residues long. MolForge cross-references it against 0 known binders and 93 disease associations.

Target properties

Protein name	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3
UniProt accession	Q9P035
Gene	HACD3
Organism	Homo sapiens
Length	362 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9P035-F1	alphafold	PREDICTED	88.65	—

Amino-acid sequence (362 residues)

MENQVLTPHV YWAQRHRELY LRVELSDVQN PAISITENVL HFKAQGHGAK GDNVYEFHLE FLDLVKPEPV YKLTQRQVNI TVQKKVSQWW ERLTKQEKRP LFLAPDFDRW LDESDAEMEL RAKEEERLNK LRLESEGSPE TLTNLRKGYL FMYNLVQFLG FSWIFVNLTV RFCILGKESF YDTFHTVADM MYFCQMLAVV ETINAAIGVT TSPVLPSLIQ LLGRNFILFI IFGTMEEMQN KAVVFFVFYL WSAIEIFRYS FYMLTCIDMD WKVLTWLRYT LWIPLYPLGC LAEAVSVIQS IPIFNETGRF SFTLPYPVKI KVRFSFFLQI YLIMIFLGLY INFRHLYKQR RRRYGQKKKK IH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards