JNK1/MAPK8-associated membrane protein (JKAMP)

About JNK1/MAPK8-associated membrane protein

JNK1/MAPK8-associated membrane protein (JKAMP) is a protein from Homo sapiens identified by UniProt accession Q9P055, 311 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	JNK1/MAPK8-associated membrane protein
UniProt accession	Q9P055
Gene	JKAMP
Organism	Homo sapiens
Length	311 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

attention deficit hyperactivity disorder · score 0.18
substance abuse · score 0.18
antisocial behaviour measurement · score 0.18
monocyte count · score 0.11
atherosclerosis · score 0.11
body height · score 0.07
brain volume measurement · score 0.05
neurofibrillary tangles measurement · score 0.04
cortical surface area measurement · score 0.04
retinal nerve fibre layer thickness measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9P055-F1	alphafold	PREDICTED	86.39	—

Amino-acid sequence (311 residues)

MAVDIQPACL GLYCGKTLLF KNGSTEIYGE CGVCPRGQRT NAQKYCQPCT ESPELYDWLY LGFMAMLPLV LHWFFIEWYS GKKSSSALFQ HITALFECSM AAIITLLVSD PVGVLYIRSC RVLMLSDWYT MLYNPSPDYV TTVHCTHEAV YPLYTIVFIY YAFCLVLMML LRPLLVKKIA CGLGKSDRFK SIYAALYFFP ILTVLQAVGG GLLYYAFPYI ILVLSLVTLA VYMSASEIEN CYDLLVRKKR LIVLFSHWLL HAYGIISISR VDKLEQDLPL LALVPTPALF YLFTAKFTEP SRILSEGANG H

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards