Mitochondrial transcription rescue factor 1 (MTRES1)

About Mitochondrial transcription rescue factor 1

Mitochondrial transcription rescue factor 1 (MTRES1) is a protein from Homo sapiens identified by UniProt accession Q9P0P8, 240 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Mitochondrial transcription rescue factor 1
UniProt accession	Q9P0P8
Gene	MTRES1
Organism	Homo sapiens
Length	240 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

parental longevity · score 0.04
systemic juvenile idiopathic arthritis · score 0.01
hyperinsulinemic hypoglycemia, familial, 4 · score 0.00
acute myeloid leukemia · score 0.00
meningococcal infection · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9P0P8-F1	alphafold	PREDICTED	66.90	—

Amino-acid sequence (240 residues)

MAMASVKLLA GVLRKPDAWI GLWGVLRGTP SSYKLCTSWN RYLYFSSTKL RAPNYKTLFY NIFSLRLPGL LLSPECIFPF SVRLKSNIRS TKSTKKSLQK VDEEDSDEES HHDEMSEQEE ELEDDPTVVK NYKDLEKAVQ SFRYDVVLKT GLDIGRNKVE DAFYKGELRL NEEKLWKKSR TVKVGDTLDL LIGEDKEAGT ETVMRILLKK VFEEKTESEK YRVVLRRWKS LKLPKKRMSK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards