About Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (COX16) is a protein
from Homo sapiens identified by UniProt accession
Q9P0S2, 106 residues long.
MolForge cross-references it against 0 known binders and
31 disease associations.
Target properties
| Protein name | Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial |
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| UniProt accession | Q9P0S2 |
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| Gene | COX16 |
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| Organism | Homo sapiens |
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| Length | 106 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (31)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- mitochondrial complex IV deficiency, nuclear type 22 · score 0.48
- low density lipoprotein cholesterol measurement · score 0.37
- Isolated cytochrome C oxidase deficiency · score 0.37
- apolipoprotein B measurement · score 0.32
- total cholesterol measurement · score 0.26
- Encephalopathy · score 0.25
- hypertrophic cardiomyopathy · score 0.25
- aspartate aminotransferase measurement · score 0.23
- response to statin · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P0S2-F1 | alphafold | PREDICTED | 75.66 | — |
Amino-acid sequence (106 residues)
MFAPAVMRAF RKNKTLGYGV PMLLLIVGGS FGLREFSQIR YDAVKSKMDP ELEKKLKENK ISLESEYEKI KDSKFDDWKN IRGPRPWEDP DLLQGRNPES LKTKTT
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