About Docking protein 5
Docking protein 5 (DOK5) is a protein
from Homo sapiens identified by UniProt accession
Q9P104, 306 residues long.
MolForge cross-references it against 0 known binders and
60 disease associations.
Target properties
| Protein name | Docking protein 5 |
|---|
| UniProt accession | Q9P104 |
|---|
| Gene | DOK5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 306 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (60)
Diseases linked to this target (Open Targets).
- adolescent idiopathic scoliosis · score 0.33
- thyroid gland adenocarcinoma · score 0.23
- body mass index · score 0.22
- breast adenocarcinoma · score 0.18
- mathematical ability · score 0.15
- self reported educational attainment · score 0.15
- gonorrhea · score 0.07
- systemic scleroderma · score 0.06
- neoplasm · score 0.04
- cancer · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P104-F1 | alphafold | PREDICTED | 78.11 | — |
Amino-acid sequence (306 residues)
MASNFNDIVK QGYVRIRSRR LGIYQRCWLV FKKASSKGPK RLEKFSDERA AYFRCYHKVT ELNNVKNVAR LPKSTKKHAI GIYFNDDTSK TFACESDLEA DEWCKVLQME CVGTRINDIS LGEPDLLATG VEREQSERFN VYLMPSPNLD VHGECALQIT YEYICLWDVQ NPRVKLISWP LSALRRYGRD TTWFTFEAGR MCETGEGLFI FQTRDGEAIY QKVHSAALAI AEQHERLLQS VKNSMLQMKM SERAASLSTM VPLPRSAYWQ HITRQHSTGQ LYRLQDVSSP LKLHRTETFP AYRSEH
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