About GEM-interacting protein
GEM-interacting protein (GMIP) is a protein
from Homo sapiens identified by UniProt accession
Q9P107, 970 residues long.
MolForge cross-references it against 0 known binders and
56 disease associations.
Target properties
| Protein name | GEM-interacting protein |
|---|
| UniProt accession | Q9P107 |
|---|
| Gene | GMIP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 970 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (56)
Diseases linked to this target (Open Targets).
- low density lipoprotein cholesterol measurement · score 0.21
- triglyceride measurement · score 0.21
- alcohol consumption measurement · score 0.20
- alcohol drinking · score 0.20
- lymphocyte percentage of leukocytes · score 0.16
- neutrophil percentage of leukocytes · score 0.15
- mitochondrial DNA measurement · score 0.14
- basophil count · score 0.12
- basophil percentage of leukocytes · score 0.12
- eosinophil count · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P107-F1 | alphafold | PREDICTED | 68.61 | — |
Amino-acid sequence (970 residues)
MDAAEPGLPP GPEGRKRYSD IFRSLDNLEI SLGNVTLEML AGDPLLSEDP EPDKTPTATV TNEASCWSGP SPEGPVPLTG EELDLRLIRT KGGVDAALEY AKTWSRYAKE LLAWTEKRAS YELEFAKSTM KIAEAGKVSI QQQSHMPLQY IYTLFLEHDL SLGTLAMETV AQQKRDYYQP LAAKRTEIEK WRKEFKEQWM KEQKRMNEAV QALRRAQLQY VQRSEDLRAR SQGSPEDSAP QASPGPSKQQ ERRRRSREEA QAKAQEAEAL YQACVREANA RQQDLEIAKQ RIVSHVRKLV FQGDEVLRRV TLSLFGLRGA QAERGPRAFA ALAECCAPFE PGQRYQEFVR ALRPEAPPPP PPAFSFQEFL PSLNSSPLDI RKKLSGPLPP RLDENSAEPG PWEDPGTGWR WQGTPGPTPG SDVDSVGGGS ESRSLDSPTS SPGAGTRQLV KASSTGTESS DDFEERDPDL GDGLENGLGS PFGKWTLSSA AQTHQLRRLR GPAKCRECEA FMVSGTECEE CFLTCHKRCL ETLLILCGHR RLPARTPLFG VDFLQLPRDF PEEVPFVVTK CTAEIEHRAL DVQGIYRVSG SRVRVERLCQ AFENGRALVE LSGNSPHDVS SVLKRFLQEL TEPVIPFHLY DAFISLAKTL HADPGDDPGT PSPSPEVIRS LKTLLVQLPD SNYNTLRHLV AHLFRVAARF MENKMSANNL GIVFGPTLLR PPDGPRAASA IPVTCLLDSG HQAQLVEFLI VHYEQIFGMD ELPQATEPPP QDSSPAPGPL TTSSQPPPPH LDPDSQPPVL ASDPGPDPQH HSTLEQHPTA TPTEIPTPQS DQREDVAEDT KDGGGEVSSQ GPEDSLLGTQ SRGHFSRQPV KYPRGGVRPV THQLSSLALV ASKLCEETPI TSVPRGSLRG RGPSPAAASP EGSPLRRTPL PKHFEITQET ARLLSKLDSE AVPRATCCPD VQPEEAEDHL
Explore GEM-interacting protein with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets