C-type lectin domain family 1 member B (CLEC1B)

About C-type lectin domain family 1 member B

C-type lectin domain family 1 member B (CLEC1B) is a protein from Homo sapiens identified by UniProt accession Q9P126, 229 residues long. MolForge cross-references it against 0 known binders and 201 disease associations.

Target properties

Protein name	C-type lectin domain family 1 member B
UniProt accession	Q9P126
Gene	CLEC1B
Organism	Homo sapiens
Length	229 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (201)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.37
breast adenocarcinoma · score 0.23
hepatocellular carcinoma · score 0.12
neoplasm · score 0.08
eosinophil count · score 0.07
thrombocytopenia 7 · score 0.07
Rare hemorrhagic disorder due to a constitutional platelet anomaly · score 0.06
essential thrombocythemia · score 0.06
bleeding disorder, platelet-type, 24 · score 0.06
Glanzmann thrombasthenia 1 · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9P126-F1	alphafold	PREDICTED	88.18	—

Amino-acid sequence (229 residues)

MQDEDGYITL NIKTRKPALI SVGSASSSWW RVMALILLIL CVGMVVGLVA LGIWSVMQRN YLQGENENRT GTLQQLAKRF CQYVVKQSEL KGTFKGHKCS PCDTNWRYYG DSCYGFFRHN LTWEESKQYC TDMNATLLKI DNRNIVEYIK ARTHLIRWVG LSRQKSNEVW KWEDGSVISE NMFEFLEDGK GNMNCAYFHN GKMHPTFCEN KHYLMCERKA GMTKVDQLP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards