Costars family protein ABRACL (ABRACL)

About Costars family protein ABRACL

Costars family protein ABRACL (ABRACL) is a protein from Homo sapiens identified by UniProt accession Q9P1F3, 81 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.

Target properties

Protein name	Costars family protein ABRACL
UniProt accession	Q9P1F3
Gene	ABRACL
Organism	Homo sapiens
Length	81 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (48)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.30
neuroimaging measurement · score 0.30
brain volume measurement · score 0.30
total cholesterol measurement · score 0.29
neurodegenerative disease · score 0.25
body height · score 0.25
total blood protein measurement · score 0.18
high density lipoprotein cholesterol measurement · score 0.16
bone measurement · score 0.15
femoral neck bone geometry · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9P1F3-F1	alphafold	PREDICTED	94.79	—

Amino-acid sequence (81 residues)

MNVDHEVNLL VEEIHRLGSK NADGKLSVKF GVLFRDDKCA NLFEALVGTL KAAKRRKIVT YPGELLLQGV HDDVDIILLQ D

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards