About NHS-like protein 3
NHS-like protein 3 (NHSL3) is a protein
from Homo sapiens identified by UniProt accession
Q9P206, 1035 residues long.
MolForge cross-references it against 0 known binders and
43 disease associations.
Target properties
| Protein name | NHS-like protein 3 |
|---|
| UniProt accession | Q9P206 |
|---|
| Gene | NHSL3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 1035 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (43)
Diseases linked to this target (Open Targets).
- body mass index · score 0.25
- cortical surface area measurement · score 0.17
- brain measurement · score 0.16
- fat body mass · score 0.14
- type 2 diabetes mellitus · score 0.13
- lean body mass · score 0.11
- hepatocellular carcinoma · score 0.10
- body weight · score 0.09
- body fat percentage · score 0.09
- non-small cell lung carcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P206-F1 | alphafold | PREDICTED | 48.76 | — |
Amino-acid sequence (1035 residues)
MVVFVGRRLP ALLGLFKKKG SAKAENDKHL SVGPGQGPGS AVDEHQDNVF FPSGRPPHLE ELHTQAQEGL RSLQHQEKQK LNKGGWDHGD TQSIQSSRTG PDEDNISFCS QTTSYVAESS TAEDALSIRS EMIQRKGSTF RPHDSFPKSG KSGRRRRERR STVLGLPQHV QKELGLRNER EAPGTPRAPG ARDAVRIPTV DGRPRGTSGM GARVSLQALE AEAEAGAETE AMLQRHIDRV YRDDTFVGRS TGTRAPPLTR PMSLAVPGLT GGAGPAEPLS PAMSISPQAT YLSKLIPHAV LPPTVDVVAL GRCSLRTLSR CSLHSASPAS VRSLGRFSSV SSPQPRSRHP SSSSDTWSHS QSSDTIVSDG STLSSKGGSE GQPESSTASN SVVPPPQGGS GRGSPSGGST AEASDTLSIR SSGQLSGRSV SLRKLKRPPP PPRRTHSLHQ RGLAVPDGPL GLPPKPERKQ QPQLPRPPTT GGSEGAGAAP CPPNPANSWV PGLSPGGSRR PPRSPERTLS PSSGYSSQSG TPTLPPKGLA GPPASPGKAQ PPKPERVTSL RSPGASVSSS LTSLCSSSSD PAPSDRSGPQ ILTPLGDRFV IPPHPKVPAP FSPPPSKPRS PNPAAPALAA PAVVPGPVST TDASPQSPPT PQTTLTPLQE SPVISKDQSP PPSPPPSYHP PPPPTKKPEV VVEAPSASET AEEPLQDPNW PPPPPPAPEE QDLSMADFPP PEEAFFSVAS PEPAGPSGSP ELVSSPAASS SSATALQIQP PGSPDPPPAP PAPAPASSAP GHVAKLPQKE PVGCSKGGGP PREDVGAPLV TPSLLQMVRL RSVGAPGGAP TPALGPSAPQ KPLRRALSGR ASPVPAPSSG LHAAVRLKAC SLAASEGLSS AQPNGPPEAE PRPPQSPAST ASFIFSKGSR KLQLERPVSP ETQADLQRNL VAELRSISEQ RPPQAPKKSP KAPPPVARKP SVGVPPPASP SYPRAEPLTA PPTNGLPHTQ DRTKRELAEN GGVLQLVGPE EKMGLPGSDS QKELA
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