About Stromal interaction molecule 2
Stromal interaction molecule 2 (STIM2) is a protein
from Homo sapiens identified by UniProt accession
Q9P246, 746 residues long.
MolForge cross-references it against 0 known binders and
115 disease associations.
Target properties
| Protein name | Stromal interaction molecule 2 |
|---|
| UniProt accession | Q9P246 |
|---|
| Gene | STIM2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 746 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P246-F1 | alphafold | PREDICTED | 65.00 | — |
Amino-acid sequence (746 residues)
MLVLGLLVAG AADGCELVPR HLRGRRATGS AATAASSPAA AAGDSPALMT DPCMSLSPPC FTEEDRFSLE ALQTIHKQMD DDKDGGIEVE ESDEFIREDM KYKDATNKHS HLHREDKHIT IEDLWKRWKT SEVHNWTLED TLQWLIEFVE LPQYEKNFRD NNVKGTTLPR IAVHEPSFMI SQLKISDRSH RQKLQLKALD VVLFGPLTRP PHNWMKDFIL TVSIVIGVGG CWFAYTQNKT SKEHVAKMMK DLESLQTAEQ SLMDLQERLE KAQEENRNVA VEKQNLERKM MDEINYAKEE ACRLRELREG AECELSRRQY AEQELEQVRM ALKKAEKEFE LRSSWSVPDA LQKWLQLTHE VEVQYYNIKR QNAEMQLAIA KDEAEKIKKK RSTVFGTLHV AHSSSLDEVD HKILEAKKAL SELTTCLRER LFRWQQIEKI CGFQIAHNSG LPSLTSSLYS DHSWVVMPRV SIPPYPIAGG VDDLDEDTPP IVSQFPGTMA KPPGSLARSS SLCRSRRSIV PSSPQPQRAQ LAPHAPHPSH PRHPHHPQHT PHSLPSPDPD ILSVSSCPAL YRNEEEEEAI YFSAEKQWEV PDTASECDSL NSSIGRKQSP PLSLEIYQTL SPRKISRDEV SLEDSSRGDS PVTVDVSWGS PDCVGLTETK SMIFSPASKV YNGILEKSCS MNQLSSGIPV PKPRHTSCSS AGNDSKPVQE APSVARISSI PHDLCHNGEK SKKPSKIKSL FKKKSK
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