Zinc finger protein 492 (ZNF492)

About Zinc finger protein 492

Zinc finger protein 492 (ZNF492) is a protein from Homo sapiens identified by UniProt accession Q9P255, 531 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

Target properties

Protein name	Zinc finger protein 492
UniProt accession	Q9P255
Gene	ZNF492
Organism	Homo sapiens
Length	531 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (10)

Diseases linked to this target (Open Targets).

upper extremity fracture · score 0.06
Down syndrome · score 0.04
hepatocellular carcinoma · score 0.01
sclerosing cholangitis · score 0.00
uterine leiomyosarcoma · score 0.00
type 2 diabetes mellitus · score 0.00
neoplasm · score 0.00
nonpapillary renal cell carcinoma · score 0.00
chronic hepatitis B virus infection · score 0.00
breast angiosarcoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9P255-F1	alphafold	PREDICTED	72.99	—

Amino-acid sequence (531 residues)

MLENYRNLVF VGIAASKPDL ITCLEQGKEP WNVKRHEMVA EPPVVCSYFA RDLWPKQGKK NYFQKVILRR YKKCGCENLQ LRKYCKSMDE CKVHKECYNG LNQCLTTTQN KIFQCDKYVK VFHKFSNSNR HTIRHTGKKS FKCKECEKSF CMLSHLAQHK RIHSGEKPYK CKECGKAYNE TSNLSTHKRI HTGKKPYKCE ECGKAFNRLS HLTTHKIIHT GKKPYKCEEC GKAFNQSANL TTHKRIHTGE KPYKCEECGR AFSQSSTLTA HKIIHAGEKP YKCEECGKAF SQSSTLTTHK IIHTGEKFYK CEECGKAFSQ LSHLTTHKRI HSGEKPYKCE ECGKAFKQSS TLTTHKRIHA GEKFYKCEVC SKAFSRFSHL TTHKRIHTGE KPYKCEECGK AFNLSSQLTT HKIIHTGEKP YKCEECGKAF NQSSTLSKHK VIHTGEKPYK YEECGKAFNQ SSHLTTHKMI HTGEKPYKCE ECGKAFNNSS ILNRHKMIHT GEKLYKPESC NNACDNIAKI SKYKRNCAGE K

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards