Protein RCC2 (RCC2)

About Protein RCC2

Protein RCC2 (RCC2) is a protein from Homo sapiens identified by UniProt accession Q9P258, 522 residues long. MolForge cross-references it against 0 known binders and 102 disease associations.

Target properties

Protein name	Protein RCC2
UniProt accession	Q9P258
Gene	RCC2
Organism	Homo sapiens
Length	522 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (102)

Diseases linked to this target (Open Targets).

basal cell carcinoma · score 0.40
skin cancer · score 0.34
non-melanoma skin carcinoma · score 0.34
appendicular lean mass · score 0.33
mean platelet volume · score 0.30
cancer · score 0.29
neurodegenerative disease · score 0.29
skin carcinoma · score 0.26
keratinocyte carcinoma · score 0.26
skin neoplasm · score 0.25

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9P258-F1	alphafold	PREDICTED	88.08	—

Amino-acid sequence (522 residues)

MPRKKAAAAA WEEPSSGNGT ARAGPRKRGG PAGRKRERPE RCSSSSGGGS SGDEDGLELD GAPGGGKRAA RPATAGKAGG AAVVITEPEH TKERVKLEGS KCKGQLLIFG ATNWDLIGRK EVPKQQAAYR NLGQNLWGPH RYGCLAGVRV RTVVSGSCAA HSLLITTEGK LWSWGRNEKG QLGHGDTKRV EAPRLIEGLS HEVIVSAACG RNHTLALTET GSVFAFGENK MGQLGLGNQT DAVPSPAQIM YNGQPITKMA CGAEFSMIMD CKGNLYSFGC PEYGQLGHNS DGKFIARAQR IEYDCELVPR RVAIFIEKTK DGQILPVPNV VVRDVACGAN HTLVLDSQKR VFSWGFGGYG RLGHAEQKDE MVPRLVKLFD FPGRGASQIY AGYTCSFAVS EVGGLFFWGA TNTSRESTMY PKAVQDLCGW RIRSLACGKS SIIVAADEST ISWGPSPTFG ELGYGDHKPK SSTAAQEVKT LDGIFSEQVA MGYSHSLVIA RDESETEKEK IKKLPEYNPR TL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards