About Junctional cadherin 5-associated protein
Junctional cadherin 5-associated protein (JCAD) is a protein
from Homo sapiens identified by UniProt accession
Q9P266, 1359 residues long.
MolForge cross-references it against 0 known binders and
127 disease associations.
Target properties
| Protein name | Junctional cadherin 5-associated protein |
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| UniProt accession | Q9P266 |
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| Gene | JCAD |
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| Organism | Homo sapiens |
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| Length | 1359 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P266-F1 | alphafold | PREDICTED | 42.85 | — |
Amino-acid sequence (1359 residues)
MYSVEDLLIS HGYKLSRDPP ASREDNPKGR QAARTGTRAG QGLQNGHEDG PAALAHRKTS AGKGHVSDSE SRRSTPRGHG EPQSTSASRT SEAGFCNQPP SAWSSHPPTG NDQAYRRRGR QEARSQKPRE HENLEARGMA QAHSLPVHVR EGPWEVGGRS EHVMKKPVWE EELRMSGPAK WQNVSLESWN QPRKLGRQMS DGDGERLFQD LYPFIQGEHV LNSQNKGKSR SLPRVLSPES LSCTEIPIPL NERHSPKMPP YPPTCAPNLD STRNSEKSGC SAPFPRPKFG RPLKPPSYSS HQQSRGGADS SDSQDSQQMD AYVPRHELCL SDPGLEPPVY VPPPSYRSPP QNIPNPYLED TVPINVCGGH SQQQSPTEKA GASGQPPSGP PGTGNEYGVS PRLPQGLPAH PRPVTAYDGF VQYIPFDDPR LRHFKLAQPQ GFCEDIKLDD KSYNSSPVTA QEPAHGGMQP DGAIWNPQSL IPPSGDERGL VLADSSPRWL WGQPPGDGEN SGLPNQRDRC VARGQWPDVR GSQHGHTGRQ VSSPYSQGES TCETQTKLKK FQTGTRTKKS SKKKMNETIF CLVSIPVKSE SHLPDRDMDN NDLKPSADQK NGSDKSPALQ EQSLLSMSST DLELQALTGS MGGRTEFQKQ DLGEPEEDRQ TNDLSFIHLT KHRELKHSGS WPGHRYRDQQ TQTSFSEEPQ SSQLLPGAKL GGPSRAALSP KCSDPAASEA QTHTAFPTGD HKQRPSARNL KGHRSLSPSS NSAFSRTSLS VDQAPTPKAG RSQPCVDVHG LGAHPGPKRE VVKGEPTGPC NSKQLFGQFL LKPVSRRPWD LISQLESFNK ELQEEEESSS SSSSSSSSSE ESEAEPQQEN RAHCRQEDVG FRGNSPEMRV EPQPRMWVPE SPVCRSGRGE SKSESWSEEL QPGHPRAWPP SPGRFRVEEG GGAPFCSADG STSAEKRHLE VSNGMDELAG SPFPVTRMSS RSSDAKPLPA SYPAEPREPQ ESPKITSAFS SVKPSEAVPR KFDSGGERGA GLPLSLSNKN RGLSAPDLRS VGLTPGQEQG ASELEGSLGE ASTIEIPPGE SLQARAARIL GIEVAVESLL PGIRRAGQNQ PAEPDASACT PESPQEELLS RPAPADVPRV STDAFYGRRK CGWTKSPLFV GDRDSARRAP QAFEHSDVDG VVTSTDPVPE PEPSPLESKF FEQKDVETKP PFRSTLFHFV ERTPSVAGSE KRLRSPSKVI ESLQEKLASP PRRADPDRLM RMKEVSSVSR MRVLSFRNAD SQEDAEELKA TTRGQAGLPG GLVSPGSGDR AQRLGHSLSV SKDSISREEK EHPAAQKEKS MDQDFWCPDS YDPSRVERV
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