SLAIN motif-containing protein 2 (SLAIN2)

About SLAIN motif-containing protein 2

SLAIN motif-containing protein 2 (SLAIN2) is a protein from Homo sapiens identified by UniProt accession Q9P270, 581 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	SLAIN motif-containing protein 2
UniProt accession	Q9P270
Gene	SLAIN2
Organism	Homo sapiens
Length	581 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.49
mean platelet volume · score 0.34
Crohn's disease · score 0.33
pulse pressure measurement · score 0.07
body height · score 0.04
cholesterol-ester transfer protein deficiency · score 0.04
hypertriglyceridemia 2 · score 0.04
Combined hyperlipidemia · score 0.03
attention deficit hyperactivity disorder · score 0.03
uterine fibroid · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9P270-F1	alphafold	PREDICTED	53.73	—

Amino-acid sequence (581 residues)

MEDVNSNVNA DQEVRKLQEL VKKLEKQNEQ LRSRSGAVQG AGSLGPGSPV RAGASIPSSG AASPRGFPLG LSAKSGGGPG SGPRRTSSEE LRDATSLLAA GEGGLLDEVE PLRPDELERL SGWEEEEESW LYSSPKKKLT PMQKSVSPLV WCRQVLDYPS PDVECAKKSL IHKLDQTMSA LKRQNLYNNP FNSMSYTSPY SPNASSPYSS GFNSPSSTPV RPPIVKQLIL PGNSGNLKSS DRNPPLSPQS SIDSELSASE LDEDSIGSNY KLNDVTDVQI LARMQEESLR QEYAATTSRR SSGSSCNSTR RGTFSDQELD AQSLDDEDDN MHHAVYPAVN RFSPSPRNSP RPSPKQSPRN SPRSRSPARG IEYSRVSPQP MISRLQQPRL SLQGHPTDLQ TSNVKNEEKL RRSLPNLSRT SNTQVDSVKS SRSDSNFQVP NGGIPRMQPQ ASAIPSPGKF RSPAAPSPLA LRQPVKAFSN HGSGSPGSQE ITQLTQTTSS PGPPMVQSTV SANPPSNINS ATLTRPAGTT AMRSGLPRPS APSAGGIPVP RSKLAQPVRR SLPAPKTYGS MKDDSWKDGC Y

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards