About BAH and coiled-coil domain-containing protein 1
BAH and coiled-coil domain-containing protein 1 (BAHCC1) is a protein
from Homo sapiens identified by UniProt accession
Q9P281, 2639 residues long.
MolForge cross-references it against 0 known binders and
99 disease associations.
Target properties
| Protein name | BAH and coiled-coil domain-containing protein 1 |
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| UniProt accession | Q9P281 |
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| Gene | BAHCC1 |
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| Organism | Homo sapiens |
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| Length | 2639 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (99)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.30
- body height · score 0.29
- refractive error measurement · score 0.29
- self reported educational attainment · score 0.28
- heel bone mineral density · score 0.28
- hypertension · score 0.26
- diastolic blood pressure · score 0.26
- dentures · score 0.26
- eosinophil count · score 0.25
- BMI-adjusted hip circumference · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P281-F1 | alphafold | PREDICTED | 39.93 | — |
Amino-acid sequence (2639 residues)
MDGRDFAPPP HLLSERGSLG HRSAAAAARL APAGPAAQPP AHFQPGKYFP SPLPMASHTA SSRLMGSSPA SSFMGSFLTS SLGSAASTHP SGPSSSPPEQ AYRGSHPTTS QIWFSHSHEA PGYPRFSGSL ASTFLPVSHL DHHGNSNVLY GQHRFYGTQK DNFYLRNLPP QPTLLPANHN FPSVARAAPA HPMGSCSRDR DRGEAGSLQK GPKDFDRFLV GKELGREKAG KAAEGKERPA AEEDGGKERH KLVLPVPADG HCREGGPAPR GACEGRPKHL TSCLLNTKVL NGEMGRAALA SCAGGMLGRP GTGVVTSGRC AKEAAGPPEP GPAFSECLER RQMLHHTASY AGPPPPLSTA AGSFPCLQLH GGPDGLCPLQ DKAPRDLKAS GPTFVPSVGH LADKGRPFQA AEACAVAGEG KDRHLEGTMA PDHAAPYGVS YAHLKAEGKG ERRPGGFEAA LNPRLKGLDY LSSAGPEASF PGLPKSGLDK SGYFELPTSS QDCARPGHQD PLGGKAPQAC CTLDKTVGKE APAGPPGAQK VARIRHQQHL MAAEVEQGGI GAEAKRKSLE LASLGYSGPH LPPWGVQAGQ GTAMAISEER KAGAYLDPFG SGLQQAALLP QELPAPPDEV SAMKNLLKYS SQALVVGQKA PLVGLGGLKA SCIQQEAKFL SSKGPGQSER PDCARSREHD TTHGDGEVRQ PPVGIAVALA RQKDTVSRSE AAYGTNTARQ GRAAPAFKGG GGPRSTHALD LEAEEERTRL CDDRLGLASR ELLLQDSKDR VEFARIHPPS SCPGDLAPHL MMQSGQLGGD PAPHTHPHPP WLPRTRSPSL WMGGHSYGLG HPALHQNLPP GFPASVAGPV PSVFPLPQDA PTQLVILPSE PTPHSAPHAL ADVMDQASLW PPMYGGRGPA SHMQHPGQLP VYSRPQLLRQ QELYALQQQR AAQFQRKPED QHLDLEEPAQ EKAPKSTHKP VALTPTAPGA PSPAAGPTKL PPCCHPPDPK PPASSPTPPP RPSAPCTLNV CPASSPGPGS RVRSAEEKNG EGQQSTADII TSEPVARAHS VAHAGLEFLA SNDPSTSASQ SFGITDLPPG YLRPMAGLGF SLPSDVHSSN LEDPETMQTT APGAQPEPTR TFLPGEPPPC SPRSLEEPGL LSGAREATQD LAATPYPTER GPQGKAADPS PLEGLQELQC AALLEAGGPE ATGQAHSTQG GAREERSREE GEQGPSSGAS SQVLEQRAGS PGALEDEGEQ PAPEEDELEE DELGQQSMED SEEDCGGAPD NSHPPRALPG LDALVAATIN LGDLPSDSPP DPQPPAASGP PSTVPLPHSS GIHGIALLSE LADLAIQRQR SERTVPEEEE DVLAFNLQHL ATLATAWSLV EAAGLDSSTA PAQPPTANPC SGPRLTPRMQ ILQRKDTWTP KTKPVCPLKA AIDRLDTQEV GMRVRLAELQ RRYKEKQREL ARLQRKHDHE RDESSRSPAR RGPGRPRKRK HSSSLPAPRP TGPLPRSDGK KVKAVRTSLG LLCAELRGGS GGEPAKKRSK LERSVYAGLQ TASVEKAQCK KSSCQGGLAP SVAHRVAQLK PKVKSKGLPT GLSSFQQKEA TPGGRIREKL SRAKSAKVSG ATRHPQPKGH GSRETPRCPA QPSVAASQEA GSGYDSEDCE GLLGTEAPPR EAGLLLHTGA SVAVLGPSPS SVVKMEANQK AKKKKERQGL LGACRLSSPE SEVKIKRRSV KAKVGTTLER APGQRPPGAL GKKKAKGKAK GSLRAEPGAT PSRDALFNPS RAFACREEGS QLASERLKRA TRKGTVLQPV LRRKNGALSI TLATRNAKAI LGKGRKLSKV KHKAGKQGKG RAVSRLLESF AVEEDFEFDD NSSFSEEEED EEEEEEDSGP LSAEQSAALA RSCAIHKEDL RDGLPVLIPK EDSLLYAGSV RTLQPPDIYS IVIEGERGNR QRIYSLEQLL QEAVLDVRPQ SSRYLPPGTR VCAYWSQKSR CLYPGNVVRG ASGDEDEDLD SVVVEFDDGD TGHIAVSNVR LLPPDFKIQC TEPSPALLVS SSCRRTKKVS SEAPPPSEAA TPSLSPKAQD GPEALKTPGK KSISKDKAGK AELLTSGAKS PTGASDHFLG RRGSPLLSWS AVAQTKRKAV AAASKGPGVL QNLFQLNGSS KKLRAREALF PVHSVATPIF GNGFRADSFS SLASSYAPFV GGTGPGLPRG AHKLLRAKKA ERVEAEKGGR RRAGGEFLVK LDHEGVTSPK NKTCKALLMG DKDFSPKLGR PLPSPSYVHP ALVGKDKKGR APIPPLPMGL ALRKYAGQAE FPLPYDSDCH SSFSDEDEDG PGLAAGVPSR FLARLSVSSS SSGSSTSSSS GSVSTSSLCS SDNEDSSYSS DDEDPALLLQ TCLTHPVPTL LAQPEALRSK GSGPHAHAQR CFLSRATVAG TGAGSGPSSS SKSKLKRKEA LSFSKAKELS RRQRPPSVEN RPKISAFLPA RQLWKWSGNP TQRRGMKGKA RKLFYKAIVR GEETLRVGDC AVFLSAGRPN LPYIGRIESM WESWGSNMVV KVKWFYHPEE TKLGKRQCDG KNALYQSCHE DENDVQTISH KCQVVAREQY EQMARSRKCQ DRQDLYYLAG TYDPTTGRLV TADGVPILC
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