Armadillo repeat-containing X-linked protein 1 (ARMCX1)

Homo sapiens — UniProt Q9P291

Gene: ARMCX1Homo sapiensSwissProt reviewed

About Armadillo repeat-containing X-linked protein 1

Armadillo repeat-containing X-linked protein 1 (ARMCX1) is a protein from Homo sapiens identified by UniProt accession Q9P291, 453 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.

Target properties

Protein nameArmadillo repeat-containing X-linked protein 1
UniProt accessionQ9P291
GeneARMCX1
OrganismHomo sapiens
Length453 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (46)

Diseases linked to this target (Open Targets).

  • neoplasm · score 0.05
  • gonorrhea · score 0.05
  • Hepatic veno-occlusive disease - immunodeficiency · score 0.05
  • immunodeficiency 75 · score 0.03
  • ovarian carcinoma · score 0.03
  • endometrial carcinoma · score 0.01
  • lung carcinoma · score 0.01
  • colorectal cancer · score 0.01
  • cancer · score 0.01
  • prostate carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9P291-F1alphafoldPREDICTED72.63—

Amino-acid sequence (453 residues)

MGRTREAGCV AAGVVIGAGA CYCVYRLAWG RDENEKIWDE DEESTDTSEI GVETVKGAKT NAGAGSGAKL QGDSEVKPEV SLGLEDCPGV KEKAHSGSHS GGGLEAKAKA LFNTLKEQAS AKAGKGARVG TISGNRTLAP SLPCPGGRGG GCHPTRSGSR AGGRASGKSK GKARSKSTRA PATTWPVRRG KFNFPYKIDD ILSAPDLQKV LNILERTNDP FIQEVALVTL GNNAAYSFNQ NAIRELGGVP IIAKLIKTKD PIIREKTYNA LNNLSVNAEN QGKIKTYISQ VCDDTMVCRL DSAVQMAGLR LLTNMTVTNH YQHLLSYSFP DFFALLFLGN HFTKIQIMKL IINFTENPAM TRELVSCKVP SELISLFNKE WDREILLNIL TLFENINDNI KNEGLASSRK EFSRSSLFFL FKESGVCVKK IKALANHNDL VVKVKVLKVL TKL

Explore Armadillo repeat-containing X-linked protein 1 with MolForge

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Quick facts

UniProtQ9P291
GeneARMCX1
OrganismHomo sapiens
Length453
Binders0
Diseases46
View on UniProt