HIG1 domain family member 1B (HIGD1B)

About HIG1 domain family member 1B

HIG1 domain family member 1B (HIGD1B) is a protein from Homo sapiens identified by UniProt accession Q9P298, 99 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.

Target properties

Protein name	HIG1 domain family member 1B
UniProt accession	Q9P298
Gene	HIGD1B
Organism	Homo sapiens
Length	99 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (22)

Diseases linked to this target (Open Targets).

pulse pressure measurement · score 0.25
self reported educational attainment · score 0.11
chronotype measurement · score 0.08
white matter microstructure measurement · score 0.07
systolic blood pressure · score 0.07
cognitive function measurement · score 0.07
platelet crit · score 0.06
lung adenocarcinoma · score 0.03
gonorrhea · score 0.03
platelet component distribution width · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9P298-F1	alphafold	PREDICTED	67.80	—

Amino-acid sequence (99 residues)

MSANRRWWVP PDDEDCVSEK LLRKTRESPL VPIGLGGCLV VAAYRIYRLR SRGSTKMSIH LIHTRVAAQA CAVGAIMLGA VYTMYSDYVK RMAQDAGEK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards