About Coatomer subunit zeta-2
Coatomer subunit zeta-2 (COPZ2) is a protein
from Homo sapiens identified by UniProt accession
Q9P299, 210 residues long.
MolForge cross-references it against 0 known binders and
54 disease associations.
Target properties
| Protein name | Coatomer subunit zeta-2 |
|---|
| UniProt accession | Q9P299 |
|---|
| Gene | COPZ2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 210 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (54)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- chronotype measurement · score 0.28
- body height · score 0.21
- high density lipoprotein cholesterol measurement · score 0.18
- leukocyte count · score 0.16
- snoring measurement · score 0.15
- triglyceride measurement · score 0.14
- type 2 diabetes mellitus · score 0.13
- FEV/FVC ratio · score 0.12
- platelet count · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P299-F1 | alphafold | PREDICTED | 83.34 | — |
Amino-acid sequence (210 residues)
MQRPEAWPRP HPGEGAAAAQ AGGPAPPARA GEPSGLRLQE PSLYTIKAVF ILDNDGRRLL AKYYDDTFPS MKEQMVFEKN VFNKTSRTES EIAFFGGMTI VYKNSIDLFL YVVGSSYENE LMLMSVLTCL FESLNHMLRK NVEKRWLLEN MDGAFLVLDE IVDGGVILES DPQQVIQKVN FRADDGGLTE QSVAQVLQSA KEQIKWSLLK
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