ABI gene family member 3 (ABI3)

About ABI gene family member 3

ABI gene family member 3 (ABI3) is a protein from Homo sapiens identified by UniProt accession Q9P2A4, 366 residues long. MolForge cross-references it against 0 known binders and 83 disease associations.

Target properties

Protein name	ABI gene family member 3
UniProt accession	Q9P2A4
Gene	ABI3
Organism	Homo sapiens
Length	366 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (83)

Diseases linked to this target (Open Targets).

refractive error measurement · score 0.33
refractive error · score 0.28
monocyte count · score 0.28
male reproductive organ cancer · score 0.25
Hypermetropia · score 0.16
Myopia · score 0.16
sex hormone-binding globulin measurement · score 0.12
reticulocyte measurement · score 0.11
Abnormality of refraction · score 0.10
cancer · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9P2A4-F1	alphafold	PREDICTED	74.15	—

Amino-acid sequence (366 residues)

MAELQQLQEF EIPTGREALR GNHSALLRVA DYCEDNYVQA TDKRKALEET MAFTTQALAS VAYQVGNLAG HTLRMLDLQG AALRQVEARV STLGQMVNMH MEKVARREIG TLATVQRLPP GQKVIAPENL PPLTPYCRRP LNFGCLDDIG HGIKDLSTQL SRTGTLSRKS IKAPATPASA TLGRPPRIPE PVHLPVVPDG RLSAASSAFS LASAGSAEGV GGAPTPKGQA APPAPPLPSS LDPPPPPAAV EVFQRPPTLE ELSPPPPDEE LPLPLDLPPP PPLDGDELGL PPPPPGFGPD EPSWVPASYL EKVVTLYPYT SQKDNELSFS EGTVICVTRR YSDGWCEGVS SEGTGFFPGN YVEPSC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards