CTTNBP2 N-terminal-like protein (CTTNBP2NL)

Homo sapiens — UniProt Q9P2B4

Gene: CTTNBP2NLHomo sapiensSwissProt reviewed

About CTTNBP2 N-terminal-like protein

CTTNBP2 N-terminal-like protein (CTTNBP2NL) is a protein from Homo sapiens identified by UniProt accession Q9P2B4, 639 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein nameCTTNBP2 N-terminal-like protein
UniProt accessionQ9P2B4
GeneCTTNBP2NL
OrganismHomo sapiens
Length639 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (26)

Diseases linked to this target (Open Targets).

  • FEV/FVC ratio · score 0.37
  • neutrophil count · score 0.24
  • self reported educational attainment · score 0.22
  • leukocyte count · score 0.21
  • mathematical ability · score 0.21
  • heel bone mineral density · score 0.19
  • smoking status measurement · score 0.10
  • hemoglobin D disease · score 0.05
  • hemoglobin E-beta-thalassemia syndrome · score 0.04
  • dominant beta-thalassemia · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9P2B4-F1alphafoldPREDICTED65.91—

Amino-acid sequence (639 residues)

MNLEKLSKPE LLTLFSILEG ELEARDLVIE ALKAQHRDTF IEERYGKYNI SDPLMALQRD FETLKEKNDG EKQPVCTNPL SILKVVMKQC KNMQERMLSQ LAAAESRHRK VILDLEEERQ RHAQDTAEGD DVTYMLEKER ERLTQQLEFE KSQVKKFEKE QKKLSSQLEE ERSRHKQLSS MLVLECKKAT NKAAEEGQKA GELSLKLEKE KSRVSKLEEE LAAERKRGLQ TEAQVEKQLS EFDIEREQLR AKLNREENRT KTLKEEMESL KKIVKDLEAS HQHSSPNEQL KKPVTVSKGT ATEPLMLMSV FCQTESFPAE RTHGSNIAKM TNTGLPGPAT PAYSYAKTNG HCDPEIQTTR ELTAGNNVEN QVPPREKSVA LAQEKPVENG GCPVGIETPV PMPSPLSSSG SSLSPSSTAS SSLTSSPCSS PVLTKRLLGS SASSPGYQSS YQVGINQRFH AARHKFQSQA DQDQQASGLQ SPPSRDLSPT LIDNSAAKQL ARNTVTQVLS RFTSQQGPIK PVSPNSSPFG TDYRNLANTA NPRGDTSHSP TPGKVSSPLS PLSPGIKSPT IPRAERGNPP PIPPKKPGLT PSPSATTPLT KTHSQAASLT TAEDLASSCS SNTVVANGKD VELLLPTSS

Explore CTTNBP2 N-terminal-like protein with MolForge

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Quick facts

UniProtQ9P2B4
GeneCTTNBP2NL
OrganismHomo sapiens
Length639
Binders0
Diseases26
View on UniProt