About Cilia- and flagella-associated protein 97
Cilia- and flagella-associated protein 97 (CFAP97) is a protein
from Homo sapiens identified by UniProt accession
Q9P2B7, 532 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Cilia- and flagella-associated protein 97 |
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| UniProt accession | Q9P2B7 |
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| Gene | CFAP97 |
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| Organism | Homo sapiens |
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| Length | 532 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (30)
Diseases linked to this target (Open Targets).
- oral squamous cell carcinoma · score 0.02
- colorectal cancer · score 0.02
- Abnormal sperm morphology · score 0.01
- juvenile dermatomyositis · score 0.01
- acute quadriplegic myopathy · score 0.01
- hepatocellular carcinoma · score 0.01
- Alzheimer disease · score 0.00
- septic shock · score 0.00
- myocardial infarction · score 0.00
- chronic obstructive pulmonary disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P2B7-F1 | alphafold | PREDICTED | 57.63 | — |
Amino-acid sequence (532 residues)
MDQFGDILEG EVDHSFFDSD FEEGKKCETN SVFDKQNDDP KERIDKDTKN VNSNTGMQTT ENYLTEKGNE RNVKFPPEHP VENDVTQTVS SFSLPASSRS KKLCDVTTGL KIHVSIPNRI PKIVKEGEDD YYTDGEESSD DGKKYHVKSK SAKPSTNVKK SIRKKYCKVS SSSSSSLSSS SSGSGTDCLD AGSDSHLSDS SPSSKSSKKH VSGITLLSPK HKYKSGIKST ETQPSSTTPK CGHYPEESED TVTDVSPLST PDISPLQSFE LGIANDQKVK IKKQENVSQE IYEDVEDLKN NSKYLKAAKK GKEKHEPDVS SKSSSVLDSS LDHRHKQKVL HDTMDLNHLL KAFLQLDKKG PQKHHFDQPS VAPGKNYSFT REEVRQIDRE NQRLLKELSR QAEKPGSKST IPRSADHPPK LYHSALNRQK EQQRIERENL ALLKRLEAVK PTVGMKRSEQ LMDYHRNMGY LNSSPLSRRA RSTLGQYSPL RASRTSSATS GLSCRSERSA VDPSSGHPRR RPKPPNVRTA WL
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