Protein unc-79 homolog (UNC79)

About Protein unc-79 homolog

Protein unc-79 homolog (UNC79) is a protein from Homo sapiens identified by UniProt accession Q9P2D8, 2635 residues long. MolForge cross-references it against 0 known binders and 90 disease associations.

Target properties

Protein name	Protein unc-79 homolog
UniProt accession	Q9P2D8
Gene	UNC79
Organism	Homo sapiens
Length	2635 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (90)

Diseases linked to this target (Open Targets).

body mass index · score 0.45
body fat percentage · score 0.42
mathematical ability · score 0.39
lean body mass · score 0.39
body weight · score 0.35
fat body mass · score 0.34
IGF-1 measurement · score 0.31
body height · score 0.28
visceral adipose tissue measurement · score 0.28
serum alanine aminotransferase measurement · score 0.28

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9P2D8-F1	alphafold	PREDICTED	63.47	—

Amino-acid sequence (2635 residues)

MSTKAEQFAS KIRYLQEYHN RVLHNIYPVP SGTDIANTLK YFSQTLLSIL SRTGKKENQD ASNLTVPMTM CLFPVPFPLT PSLRPQVSSI NPTVTRSLLY SVLRDAPSER GPQSRDAQLS DYPSLDYQGL YVTLVTLLDL VPLLQHGQHD LGQSIFYTTT CLLPFLNDDI LSTLPYTMIS TLATFPPFLH KDIIEYLSTS FLPMAILGSS RREGVPAHVN LSASSMLMIA MQYTSNPVYH CQLLECLMKY KQEVWKDLLY VIAYGPSQVK PPAVQMLFHY WPNLKPPGAI SEYRGLQYTA WNPIHCQHIE CHNAINKPAV KMCIDPSLSV ALGDKPPPLY LCEECSERIA GDHSEWLIDV LLPQAEISAI CQKKNCSSHV RRAVVTCFSA GCCGRHGNRP VRYCKRCHSN HHSNEVGAAA ETHLYQTSPP PINTRECGAE ELVCAVEAVI SLLKEAEFHA EQREHELNRR RQLGLSSSHH SLDNADFDNK DDDKHDQRLL SQFGIWFLVS LCTPSENTPT ESLARLVAMV FQWFHSTAYM MDDEVGSLVE KLKPQFVTKW LKTVCDVRFD VMVMCLLPKP MEFARVGGYW DKSCSTVTQL KEGLNRILCL IPYNVINQSV WECIMPEWLE AIRTEVPDNQ LKEFREVLSK MFDIELCPLP FSMEEMFGFI SCRFTGYPSS VQEQALLWLH VLSELDIMVP LQLLISMFSD GVNSVKELAN QRKSRVSELA GNLASRRVSV ASDPGRRVQH NMLSPFHSPF QSPFRSPLRS PFRSPFKNFG HPGGRTIDFD CEDDEMNLNC FILMFDLLLK QMELQDDGIT MGLEHSLSKD IISIINNVFQ APWGGSHTCQ KDEKAIECNL CQSSILCYQL ACELLERLAP KEESRLVEPT DSLEDSLLSS RPEFIIGPEG EEEENPASKH GENPGNCTEP VEHAAVKNDT ERKFCYQQLP VTLRLIYTIF QEMAKFEEPD ILFNMLNCLK ILCLHGECLY IARKDHPQFL AYIQDHMLIA SLWRVVKSEF SQLSSLAVPL LLHALSLPHG ADIFWTIING NFNSKDWKMR FEAVEKVAVI CRFLDIHSVT KNHLLKYSLA HAFCCFLTAV EDVNPAVATR AGLLLDTIKR PALQGLCLCL DFQFDTVVKD RPTILSKLLL LHFLKQDIPA LSWEFFVNRF ETLSLEAQLH LDCNKEFPFP TTITAVRTNV ANLSDAALWK IKRARFARNR QKSVRSLRDS VKGPVESKRA LSLPETLTSK IRQQSPENDN TIKDLLPEDA GIDHQTVHQL ITVLMKFMAK DESSAESDIS SAKAFNTVKR HLYVLLGYDQ QEGCFMIAPQ KMRLSTCFNA FIAGIAQVMD YNINLGKHLL PLVVQVLKYC SCPQLRHYFQ QPPRCSLWSL KPHIRQMWLK ALLVILYKYP YRDCDISKIL LHLIHITVNT LNAQYHSCKP HATAGPLYSD NSNISRYSEK EKGEIELAEY RETGALQDSL LHCVREESIP KKKLRSFKQK SLDIGNADSL LFTLDEHRRK SCIDRCDIEK PPTQAAYIAQ RPNDPGRSRQ NSATRPDNSE IPENPAMEGF PDARRPVIPE VRLNCMETFE VKVDSPVKPA PKEDLDLIDL SSDSTSGPEK HSILSTSDSD SLVFEPLPPL RIVESDEEEE TMNQGDDGPS GKNAASSPSV PSHPSVLSLS TAPLVQVSVE DCSKDFSSKD SGNNQSAGNT DSALITLEDP MDAEGSSKPE ELPEFSCGSP LTLKQKRDLL QKSFALPEMS LDDHPDPGTE GEKPGELMPS SGAKTVLLKV PEDAENPTES EKPDTSAESD TEQNPERKVE EDGAEESEFK IQIVPRQRKQ RKIAVSAIQR EYLDISFNIL DKLGEQKDPD PSTKGLSTLE MPRESSSAPT LDAGVPETSS HSSISTQYRQ MKRGSLGVLT MSQLMKRQLE HQSSAPHNIS NWDTEQIQPG KRQCNVPTCL NPDLEGQPLR MRGATKSSLL SAPSIVSMFV PAPEEFTDEQ PTVMTDKCHD CGAILEEYDE ETLGLAIVVL STFIHLSPDL AAPLLLDIMQ SVGRLASSTT FSNQAESMMV PGNAAGVAKQ FLRCIFHQLA PNGIFPQLFQ STIKDGTFLR TLASSLMDFN ELSSIAALSQ LLEGLNNKKN LPAGGAMIRC LENIATFMEA LPMDSPSSLW TTISNQFQTF FAKLPCVLPL KCSLDSSLRI MICLLKIPST NATRSLLEPF SKLLSFVIQN AVFTLAYLVE LCGLCYRAFT KERDKFYLSR SVVLELLQAL KLKSPLPDTN LLLLVQFICA DAGTKLAEST ILSKQMIASV PGCGTAAMEC VRQYINEVLD FMADMHTLTK LKSHMKTCSQ PLHEDTFGGH LKVGLAQIAA MDISRGNHRD NKAVIRYLPW LYHPPSAMQQ GPKEFIECVS HIRLLSWLLL GSLTHNAVCP NASSPCLPIP LDAGSHVADH LIVILIGFPE QSKTSVLHMC SLFHAFIFAQ LWTVYCEQSA VATNLQNQNE FSFTAILTAL EFWSRVTPSI LQLMAHNKVM VEMVCLHVIS LMEALQECNS TIFVKLIPMW LPMIQSNIKH LSAGLQLRLQ AIQNHVNHHS LRTLPGSGQS SAGLAALRKW LQCTQFKMAQ VEIQSSEAAS QFYPL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards