About Kinesin-like protein KIF17
Kinesin-like protein KIF17 (KIF17) is a protein
from Homo sapiens identified by UniProt accession
Q9P2E2, 1029 residues long.
MolForge cross-references it against 0 known binders and
37 disease associations.
Target properties
| Protein name | Kinesin-like protein KIF17 |
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| UniProt accession | Q9P2E2 |
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| Gene | KIF17 |
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| Organism | Homo sapiens |
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| Length | 1029 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (37)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.13
- hematocrit · score 0.06
- Lewy body dementia · score 0.06
- hemoglobin measurement · score 0.05
- balding measurement · score 0.04
- body height · score 0.03
- platelet crit · score 0.02
- schizophrenia · score 0.02
- glioblastoma multiforme · score 0.02
- Malignant Bone Neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P2E2-F1 | alphafold | PREDICTED | 64.23 | — |
Amino-acid sequence (1029 residues)
MASEAVKVVV RCRPMNQRER ELRCQPVVTV DCARAQCCIQ NPGAADEPPK QFTFDGAYHV DHVTEQIYNE IAYPLVEGVT EGYNGTIFAY GQTGSGKSFT MQGLPDPPSQ RGIIPRAFEH VFESVQCAEN TKFLVRASYL EIYNEDVRDL LGADTKQKLE LKEHPEKGVY VKGLSMHTVH SVAQCEHIME TGWKNRSVGY TLMNKDSSRS HSIFTISIEM SAVDERGKDH LRAGKLNLVD LAGSERQSKT GATGERLKEA TKINLSLSAL GNVISALVDG RCKHVPYRDS KLTRLLQDSL GGNTKTLMVA CLSPADNNYD ETLSTLRYAN RAKNIRNKPR INEDPKDALL REYQEEIKKL KAILTQQMSP SSLSALLSRQ VPPDPVQVEE KLLPQPVIQH DVEAEKQLIR EEYEERLARL KADYKAEQES RARLEEDITA MRNSYDVRLS TLEENLRKET EAVLQVGVLY KAEVMSRAEF ASSAEYPPAF QYETVVKPKV FSTTDTLPSD DVSKTQVSSR FAELPKVEPS KSEISLGSSE SSSLEETSVS EAFPGPEEPS NVEVSMPTEE SRSRYFLDEC LGQEAAGHLL GEQNYLPQEE PQEVPLQGLL GLQDPFAEVE AKLARLSSTV ARTDAPQADV PKVPVQVPAP TDLLEPSDAR PEAEAADDFP PRPEVDLASE VALEVVRTAE PGVWLEAQAP VALVAQPEPL PATAGVKRES VGMEVAVLTD DPLPVVDQQQ VLARLQLLEQ QVVGGEQAKN KDLKEKHKRR KRYADERRKQ LVAALQNSDE DSGDWVLLNV YDSIQEEVRA KSKLLEKMQR KLRAAEVEIK DLQSEFQLEK IDYLATIRRQ ERDSMLLQQL LEQVQPLIRR DCNYSNLEKI LRESCWDEDN GFWKIPHPVI TKTSLPVAVS TGPQNKPARK TSAADNGEPN MEDDRYRLML SRSNSENIAS NYFRSKRASQ ILSTDARKSL THHNSPPGLS CPLSNNSAIP PTQAPEMPQP RPFRLESLDI PFTKAKRKKS KSNFGSEPL
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