About NFX1-type zinc finger-containing protein 1
NFX1-type zinc finger-containing protein 1 (ZNFX1) is a protein
from Homo sapiens identified by UniProt accession
Q9P2E3, 1918 residues long.
MolForge cross-references it against 0 known binders and
74 disease associations.
Target properties
| Protein name | NFX1-type zinc finger-containing protein 1 |
|---|
| UniProt accession | Q9P2E3 |
|---|
| Gene | ZNFX1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 1918 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (74)
Diseases linked to this target (Open Targets).
- immunodeficiency 91 and hyperinflammation · score 0.63
- Mendelian susceptibility to mycobacterial diseases · score 0.37
- electrocardiography · score 0.31
- body height · score 0.29
- triglyceride measurement · score 0.24
- genetic disorder · score 0.19
- BMI-adjusted waist circumference · score 0.17
- lean body mass · score 0.15
- wellbeing measurement · score 0.13
- undetermined early-onset epileptic encephalopathy · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P2E3-F1 | alphafold | PREDICTED | 73.87 | — |
Amino-acid sequence (1918 residues)
MEERRPHLDA RPRNSHTNHR GPVDGELPPR ARNQANNPPA NALRGGASHP GRHPRANNHP AAYWQREERF RAMGRNPHQG RRNQEGHASD EARDQRHDQE NDTRWRNGNQ DCRNRRPPWS NDNFQQWRTP HQKPTEQPQQ AKKLGYKFLE SLLQKDPSEV VITLATSLGL KELLSHSSMK SNFLELICQV LRKACSSKMD RQSVLHVLGI LKNSKFLKVC LPAYVVGMIT EPIPDIRNQY PEHISNIISL LQDLVSVFPA SSVQETSMLV SLLPTSLNAL RASGVDIEEE TEKNLEKVQT IIEHLQEKRR EGTLRVDTYT LVQPEAEDHV ESYRTMPIYP TYNEVHLDER PFLRPNIISG KYDSTAIYLD THFRLLREDF VRPLREGILE LLQSFEDQGL RKRKFDDIRI YFDTRIITPM CSSSGIVYKV QFDTKPLKFV RWQNSKRLLY GSLVCMSKDN FETFLFATVS NREQEDLCRG IVQLCFNEQS QQLLAEVQPS DSFLMVETTA YFEAYRHVLE GLQEVQEEDV PFQRNIVECN SHVKEPRYLL MGGRYDFTPL IENPSATGEF LRNVEGLRHP RINVLDPGQW PSKEALKLDD SQMEALQFAL TRELAIIQGP PGTGKTYVGL KIVQALLTNE SVWQISLQKF PILVVCYTNH ALDQFLEGIY NCQKTSIVRV GGRSNSEILK QFTLRELRNK REFRRNLPMH LRRAYMSIMT QMKESEQELH EGAKTLECTM RGVLREQYLQ KYISPQHWES LMNGPVQDSE WICFQHWKHS MMLEWLGLGV GSFTQSVSPA GPENTAQAEG DEEEEGEEES SLIEIAEEAD LIQADRVIEE EEVVRPQRRK KEESGADQEL AKMLLAMRLD HCGTGTAAGQ EQATGEWQTQ RNQKKKMKKR VKDELRKLNT MTAAEANEIE DVWQLDLSSR WQLYRLWLQL YQADTRRKIL SYERQYRTSA ERMAELRLQE DLHILKDAQV VGMTTTGAAK YRQILQKVEP RIVIVEEAAE VLEAHTIATL SKACQHLILI GDHQQLRPSA NVYDLAKNFN LEVSLFERLV KVNIPFVRLN YQHRMCPEIA RLLTPHIYQD LENHPSVLKY EKIKGVSSNL FFVEHNFPEQ EIQEGKSHQN QHEAHFVVEL CKYFLCQEYL PSQITILTTY TGQLFCLRKL MPAKTFAGVR VHVVDKYQGE ENDIILLSLV RSNQEGKVGF LQISNRICVA LSRAKKGMYC IGNMQMLAKV PLWSKIIHTL RENNQIGPML RLCCQNHPET HTLVSKASDF QKVPEGGCSL PCEFRLGCGH VCTRACHPYD SSHKEFQCMK PCQKVICQEG HRCPLVCFQE CQPCQVKVPK TIPRCGHEQM VPCSVPESDF CCQEPCSKSL RCGHRCSHPC GEDCVQLCSE MVTIKLKCGH SQPVKCGHVE GLLYGGLLVK CTTKCGTILD CGHPCPGSCH SCFEGRFHER CQQPCKRLLI CSHKCQEPCI GECPPCQRTC QNRCVHSQCK KKCGELCSPC VEPCVWRCQH YQCTKLCSEP CNRPPCYVPC TKLLVCGHPC IGLCGEPCPK KCRICHMDEV TQIFFGFEDE PDARFVQLED CSHIFEVQAL DRYMNEQKDD EVAIRLKVCP ICQVPIRKNL RYGTSIKQRL EEIEIIKEKI QGSAGEIATS QERLKALLER KSLLHQLLPE DFLMLKEKLA QKNLSVKDLG LVENYISFYD HLASLWDSLK KMHVLEEKRV RTRLEQVHEW LAKKRLSFTS QELSDLRSEI QRLTYLVNLL TRYKIAEKKV KDSIAVEVYS VQNILEKTCK FTQEDEQLVQ EKMEALKATL PCSGLGISEE ERVQIVSAIG YPRGHWFKCR NGHIYVIGDC GGAMERGTCP DCKEVIGGTN HTLERSNQLA SEMDGAQHAA WSDTANNLMN FEEIQGMM
Explore NFX1-type zinc finger-containing protein 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets