About Protocadherin-10
Protocadherin-10 (PCDH10) is a protein
from Homo sapiens identified by UniProt accession
Q9P2E7, 1040 residues long.
MolForge cross-references it against 0 known binders and
100 disease associations.
Target properties
| Protein name | Protocadherin-10 |
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| UniProt accession | Q9P2E7 |
|---|
| Gene | PCDH10 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 1040 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (100)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.22
- insomnia · score 0.22
- total blood protein measurement · score 0.22
- neoplasm · score 0.10
- hepatocellular carcinoma · score 0.10
- gonorrhea · score 0.09
- Miyoshi myopathy · score 0.06
- attention deficit hyperactivity disorder · score 0.06
- gait measurement · score 0.05
- DNA methylation · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P2E7-F1 | alphafold | PREDICTED | 73.20 | — |
Amino-acid sequence (1040 residues)
MIVLLLFALL WMVEGVFSQL HYTVQEEQEH GTFVGNIAED LGLDITKLSA RGFQTVPNSR TPYLDLNLET GVLYVNEKID REQICKQSPS CVLHLEVFLE NPLELFQVEI EVLDINDNPP SFPEPDLTVE ISESATPGTR FPLESAFDPD VGTNSLRDYE ITPNSYFSLD VQTQGDGNRF AELVLEKPLD REQQAVHRYV LTAVDGGGGG GVGEGGGGGG GAGLPPQQQR TGTALLTIRV LDSNDNVPAF DQPVYTVSLP ENSPPGTLVI QLNATDPDEG QNGEVVYSFS SHISPRAREL FGLSPRTGRL EVSGELDYEE SPVYQVYVQA KDLGPNAVPA HCKVLVRVLD ANDNAPEISF STVKEAVSEG AAPGTVVALF SVTDRDSEEN GQVQCELLGD VPFRLKSSFK NYYTIVTEAP LDREAGDSYT LTVVARDRGE PALSTSKSIQ VQVSDVNDNA PRFSQPVYDV YVTENNVPGA YIYAVSATDR DEGANAQLAY SILECQIQGM SVFTYVSINS ENGYLYALRS FDYEQLKDFS FQVEARDAGS PQALAGNATV NILIVDQNDN APAIVAPLPG RNGTPAREVL PRSAEPGYLL TRVAAVDADD GENARLTYSI VRGNEMNLFR MDWRTGELRT ARRVPAKRDP QRPYELVIEV RDHGQPPLSS TATLVVQLVD GAVEPQGGGG SGGGGSGEHQ RPSRSGGGET SLDLTLILII ALGSVSFIFL LAMIVLAVRC QKEKKLNIYT CLASDCCLCC CCCGGGGSTC CGRQARARKK KLSKSDIMLV QSSNVPSNPA QVPIEESGGF GSHHHNQNYC YQVCLTPESA KTDLMFLKPC SPSRSTDTEH NPCGAIVTGY TDQQPDIISN GSILSNETKH QRAELSYLVD RPRRVNSSAF QEADIVSSKD SGHGDSEQGD SDHDATNRAQ SAGMDLFSNC TEECKALGHS DRCWMPSFVP SDGRQAADYR SNLHVPGMDS VPDTEVFETP EAQPGAERSF STFGKEKALH STLERKELDG LLTNTRAPYK PPYLTRKRIC
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