About Storkhead-box protein 2
Storkhead-box protein 2 (STOX2) is a protein
from Homo sapiens identified by UniProt accession
Q9P2F5, 926 residues long.
MolForge cross-references it against 0 known binders and
56 disease associations.
Target properties
| Protein name | Storkhead-box protein 2 |
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| UniProt accession | Q9P2F5 |
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| Gene | STOX2 |
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| Organism | Homo sapiens |
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| Length | 926 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (56)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.45
- self reported educational attainment · score 0.33
- emotional symptom measurement · score 0.33
- intraocular pressure measurement · score 0.32
- alcohol consumption measurement · score 0.32
- refractive error measurement · score 0.31
- retinal layer thickness measurement · score 0.30
- ganglion cell inner plexiform layer thickness measurement · score 0.29
- cognitive function measurement · score 0.27
- macula measurement · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P2F5-F1 | alphafold | PREDICTED | 49.84 | — |
Amino-acid sequence (926 residues)
MKKTRSTTLR RAWPSSDFSD RASDRMRSRS EKDYRLHKRF PAAFAPQASR GYMTSGDVSP ISMSPISQSQ FIPLGEILCL AISAMNSARK PVTQEALMEH LTTCFPGVPT PSQEILRHTL NTLVRERKIY PTPDGYFIVT PQTYFITPSL IRTNSKWYHL DERIPDRSQC TSPQPGTITP SASGCVRERT LPRNHCDSCH CCREDVHSTH APTLQRKSAK DCKDPYCPPS LCQVPPTEKS KSTVNFSYKT ETLSKPKDSE KQSKKFGLKL FRLSFKKDKT KQLANFSAQF PPEEWPLRDE DTPATIPREV EMEIIRRINP DLTVENVMRH TALMKKLEEE KAQRSKAGSS AHHSGRSKKS RTHRKSHGKS RSHSKTRVSK GDPSDGSHLD IPAEREYDFC DPLTRVPREG CFIIEHKGDN FIMHSNTNVL ESHFPMTPEW DVSGELAKRR TEMPFPEPSR GSSHSKVHRS HSHTQDRRSR NERSNKAKER SRSMDNSKGP LGASSLGTPE DLAEGCSQDD QTPSQSYIDD STLRPAQTVS LQRAHISSTS YKEVCIPEIV SGSKEPSSAC SLLEPGKPPE SLPSYGELNS CPTKTATDDY FQCNTSSETV LTAPSPLGKN KEDHDTLTLA EGVKKLSPSD RQVPHSSREP VGHKEESPKG PGGGPAASGG VAEGIANGRL VQHHGAEPSS LDKRKEIFSK DTLFKPLHST LSVNSYHKSS LSLLKSHPKT PADTLPGRCE KLEPSLGTSA AQAMPASQRQ QESGGNQEAS FDYYNVSDDD DSEEGANKNT EEEKNREDVG TMQWLLEREK ERDLQRKFEK NLTLLAPKET DSSSNQRATH SARLDSMDSS SITVDSGFNS PRTRESLASN TSSIVESNRR QNPALSPAHG GAGPAFNFRA SAEPPTNEAE KLQKPSNCLQ ASVTSV
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