About Microtubule-associated protein 10
Microtubule-associated protein 10 (MAP10) is a protein
from Homo sapiens identified by UniProt accession
Q9P2G4, 905 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | Microtubule-associated protein 10 |
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| UniProt accession | Q9P2G4 |
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| Gene | MAP10 |
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| Organism | Homo sapiens |
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| Length | 905 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (13)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.31
- hemoglobin measurement · score 0.29
- hematocrit · score 0.04
- serum gamma-glutamyl transferase measurement · score 0.04
- red blood cell density measurement · score 0.03
- obstructive sleep apnea · score 0.01
- cancer · score 0.01
- diabetes mellitus · score 0.01
- endometrial carcinoma · score 0.01
- Sepsis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P2G4-F1 | alphafold | PREDICTED | 50.31 | — |
Amino-acid sequence (905 residues)
MAASLSERLF SLELLVDWVR LEARLLPSPA AAVEQEEEEE EKEQGEASSP RGLCPAVAFR LLDFPTLLVY PPDGPGAPAA EPWPGVIRFG RGKSCLFRLQ PATLHCRLLR TPLATLLLQL PPGRPTPTPQ LLGACDISLA TAAHRVVGPA ASGCSHRHRG RFPLHNRVGE RTGDIALAYR LTDLGSRLLS QLERPLTFTR TGGGAEVSPQ TQQERQQLQQ PASQPSPKEA DKPLGELEIP EAQKDLKEMV KSKAECDNVG SVENGKTNSV VTCSGAGNGR NVSSLNEEVT ELDMETNIFC PPPLYYTNLT QEKPPPAQAK ITIEPQMNAP EEMDDASPEK KRVNPPAHRS CLKHPSSAAH EHPPMLVNPP HIQNIGATNQ TCQTEQNRIN TIRQLPLLNA LLVELSLLYD QPVTSPAHIH PHLAWLYRTE DKKSPESSAK STCRSEAKKD KRSVGGCEKS VSLQYKKNQI ENYKEDKYSE KSSGALHKRV PKGRLLYGLT NTLRLRLKLT NPDMLVVHEK RELYRKRQSQ MLGTKFRIPS SKVKLLSSAE QSQKPQLPED KYLDSDASFT ENSDTSRQIS GVFDEPSTSK ETKLKYATEK KTVDCSKNRI NNVSLEEVVS PANSIIPERL TPTNILGGNV EMKIQSPCVF QQDAVVDRIV DKEIDIRQVK TTDNDILMAD ISDKRTGKNS CYENISELKY SDDLSSPCYS EDFCTSEDTS RSFKAHDSSS RTENPKHSQY TSKSSDTGVS KKKNSSDRSS ILSPPFSAGS PVHSYRKFHI SKTQDKSLEE ASSISASDLS STHWTEQKEN QIDQNSMHNS EITKRAQDIS VKTRSSWKSL EKSQSPQTSQ VSSYLPSNVS ELNVLDSSTS DHFEEGNDDV GSLNISKQCK DICELVINKL PGYTM
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