About LRP2-binding protein
LRP2-binding protein (LRP2BP) is a protein
from Homo sapiens identified by UniProt accession
Q9P2M1, 347 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | LRP2-binding protein |
|---|
| UniProt accession | Q9P2M1 |
|---|
| Gene | LRP2BP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 347 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- systemic scleroderma · score 0.07
- mean platelet volume · score 0.02
- childhood trauma measurement · score 0.02
- smoking behaviour measurement · score 0.02
- ependymoma · score 0.02
- Pick disease · score 0.00
- metopic craniosynostosis · score 0.00
- progressive supranuclear palsy · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P2M1-F1 | alphafold | PREDICTED | 92.78 | — |
Amino-acid sequence (347 residues)
MKLTSEKLPK NPFYASVSQY AAKNQKFFQW KKEKTDYTHA NLVDKALQLL KERILKGDTL AYFLRGQLYF EEGWYEEALE QFEEIKEKDH QATYQLGVMY YDGLGTTLDA EKGVDYMKKI LDSPCPKARH LKFAAAYNLG RAYYEGKGVK RSNEEAERLW LIAADNGNPK ASVKAQSMLG LYYSTKEPKE LEKAFYWHSE ACGNGNLESQ GALGLMYLYG QGIRQDTEAA LQCLREAAER GNVYAQGNLV EYYYKMKFFT KCVAFSKRIA DYDEVHDIPM IAQVTDCLPE FIGRGMAMAS FYHARCLQLG LGITRDETTA KHYYSKACRL NPALADELHS LLIRQRI
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