About KAT8 regulatory NSL complex subunit 3
KAT8 regulatory NSL complex subunit 3 (KANSL3) is a protein
from Homo sapiens identified by UniProt accession
Q9P2N6, 904 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | KAT8 regulatory NSL complex subunit 3 |
|---|
| UniProt accession | Q9P2N6 |
|---|
| Gene | KANSL3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 904 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (29)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.26
- breast adenocarcinoma · score 0.22
- body height · score 0.12
- BMI-adjusted hip circumference · score 0.11
- eosinophil percentage of leukocytes · score 0.11
- sum of eosinophil and basophil counts · score 0.10
- eosinophil percentage of granulocytes · score 0.10
- sex hormone-binding globulin measurement · score 0.09
- appendicular lean mass · score 0.08
- neutrophil percentage of granulocytes · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P2N6-F1 | alphafold | PREDICTED | 60.12 | — |
Amino-acid sequence (904 residues)
MAHRGGERDF QTSARRMGTS LLFQLSVHER ELDLVFLDHS YAKPWSAHPD ASSARPTRML FVTPRRQHES TIESDVPIDV ETVTSTPMPL YDNQKARSVM NECERHVIFA RTDADAPPPP EDWEEHVNRT GWTMAQNKLF NKILKALQSD RLARLANEGA CNEPVLRRVA VDKCARRVRQ ALASVSWDTK LIQWLHTTLV ETLSLPMLAA YLDALQTLKG KIPTLIDRML VSSNTKTGAA GAEALSLLLK RPWDPAVGVL SHNKPSKLPG SPLILIASSG PSSSVFPTSR RHRFWQSQLS CLGKVIPVAT HLLNNGSGVG VLQCLEHMIG AVRSKVLEIH SHFPHKPIIL IGWNTGALVA CHVSVMEYVT AVVCLGFPLL TVDGPRGDVD DPLLDMKTPV LFVIGQNSLQ CHPEAMEDFR EKIRAENSLV VVGGADDNLR ISKAKKKSEG LTQSMVDRCI QDEIVDFLTG VLTRAEGHMG SEPRDQDAEK KKKPRDVARR DLAFEVPERG SRPASPAAKL PASPSGSEDL SSVSSSPTSS PKTKVTTVTS AQKSSQIGSS QLLKRHVQRT EAVLTHKQAQ AQFAAFLKQN MLVRKALPPG TSSCLFVPIS SEPPEEGEKE DLRVQLKRHH PSSPLPGSKT SKRPKIKVSL ISQGDTAGGP CAPSQGSAPE AAGGKPITMT LGQASAGAKE LTGLLTTAKS SSSEGGVSAS PVPSVVSSST APSALHTLQS RLVATSPGSS LPGATSASSL LQGLSFSLQD ISSKTSGLPA NPSPGPAPQA TSVKLPTPMQ SLGAITTGTS TIVRTIPVAT TLSSLGATPG GKPTAIHQLL TNGGLAKLAS SLPGLAQISN QASGLKVPTT ITLTLRGQPS RITTLSPMGS GAAPSEESSS QVLPSSSQRL PPAP
Explore KAT8 regulatory NSL complex subunit 3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets