About Ankyrin repeat and MYND domain-containing protein 1
Ankyrin repeat and MYND domain-containing protein 1 (ANKMY1) is a protein
from Homo sapiens identified by UniProt accession
Q9P2S6, 941 residues long.
MolForge cross-references it against 0 known binders and
27 disease associations.
Target properties
| Protein name | Ankyrin repeat and MYND domain-containing protein 1 |
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| UniProt accession | Q9P2S6 |
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| Gene | ANKMY1 |
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| Organism | Homo sapiens |
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| Length | 941 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (27)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin · score 0.33
- mean platelet volume · score 0.29
- hemolytic anemia · score 0.28
- platelet count · score 0.11
- erythrocyte count · score 0.11
- mean corpuscular hemoglobin concentration · score 0.11
- blood protein measurement · score 0.10
- reticulocyte count · score 0.10
- hematocrit · score 0.10
- mean corpuscular volume · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P2S6-F1 | alphafold | PREDICTED | 77.72 | — |
Amino-acid sequence (941 residues)
MYQGEFGLNM KLGYGKFSWP TGESYHGQFY RDHCHGLGTY MWPDGSSFTG TFYLSHREGY GTMYMKTRLF QGLYKADQRF GPGVETYPDG SQDVGLWFRE QLIKLCTQIP SGFSLLRYPE FSSFITHSPA RISLSEEEKT EWGLQEGQDP FFYDYKRFLL NDNLTLPPEM YVYSTNSDHL PMTSSFRKEL DARIFLNEIP PFVEDGEPWF IINETPLLVK IQKQTYKFRN KPAHTSWNMG AILEGKRSGF APCGPKEQLS MEMILKAEEG NHEWICRILK DNFASADVAD AKGYTVLAAA ATHCHNDIVN LLLDCGADVN KCSDEGLTAL SMCFLLHYPA QSFKPNVAER TIPEPQEPPK FPVVPILSSS FMDTNLESLY YEVNVPSQGS YELRPPPAPL LLPRVSGSHE GGHFQDTGQC GGSIDHRSSS LKGDSPLVKG SLGHVESGLE DVLGNTDRGS LCSAETKFES NVCVCDFSIE LSQAMLERSA QSHSLLKMAS PSPCTSSFDK GTMRRMALSM IERRKRWRTI KLLLRRGADP NLCCVPMQVL FLAVKAGDVD GVRLLLEHGA RTDICFPPQL STLTPLHIAA ALPGEEGVQI VELLLHAITD VDAKASDEDD TYKPGKLDLL PSSLKLSNEP GPPQAYYSTD TALPEEGGRT ALHMACERED DNKCARDIVR LLLSHGANPN LLWSGHSPLS LSIASGNELV VKELLTQGAD PNLPLTKGLG SALCVACDLT YEHQRNMDSK LALIDRLISH GADILKPVML RQGEKEAVGT AVDYGYFRFF QDRRIARCPF HTLMPAERET FLARKRLLEY MGLQLRQAVF AKESQWDPTW LYLCKRAELI PSHRMKKKGP SLPRGLDVKE QGQIPFFKFC YQCGRSIGVR LLPCPRCYGI LTCSKYCKTK AWTEFHKKDC GDLVAIVTQL EQVSRRREEF Q
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