About Protein IMPACT
Protein IMPACT (IMPACT) is a protein
from Homo sapiens identified by UniProt accession
Q9P2X3, 320 residues long.
MolForge cross-references it against 0 known binders and
69 disease associations.
Target properties
| Protein name | Protein IMPACT |
|---|
| UniProt accession | Q9P2X3 |
|---|
| Gene | IMPACT |
|---|
| Organism | Homo sapiens |
|---|
| Length | 320 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (69)
Diseases linked to this target (Open Targets).
- body mass index · score 0.31
- nasopharyngeal neoplasm · score 0.29
- body fat percentage · score 0.29
- lean body mass · score 0.27
- vital capacity · score 0.26
- forced expiratory volume · score 0.23
- visceral adipose tissue measurement · score 0.20
- body height · score 0.20
- self reported educational attainment · score 0.16
- cortical thickness · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9P2X3-F1 | alphafold | PREDICTED | 80.18 | — |
Amino-acid sequence (320 residues)
MAEGDAGSDQ RQNEEIEAMA AIYGEEWCVI DDCAKIFCIR ISDDIDDPKW TLCLQVMLPN EYPGTAPPIY QLNAPWLKGQ ERADLSNSLE EIYIQNIGES ILYLWVEKIR DVLIQKSQMT EPGPDVKKKT EEEDVECEDD LILACQPESS LKALDFDISE TRTEVEVEEL PPIDHGIPIT DRRSTFQAHL APVVCPKQVK MVLSKLYENK KIASATHNIY AYRIYCEDKQ TFLQDCEDDG ETAAGGRLLH LMEILNVKNV MVVVSRWYGG ILLGPDRFKH INNCARNILV EKNYTNSPEE SSKALGKNKK VRKDKKRNEH
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