About Heat shock transcription factor, X-linked
Heat shock transcription factor, X-linked (HSFX1) is a protein
from Homo sapiens identified by UniProt accession
Q9UBD0, 423 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Heat shock transcription factor, X-linked |
|---|
| UniProt accession | Q9UBD0 |
|---|
| Gene | HSFX1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 423 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- lung adenocarcinoma · score 0.01
- neoplasm · score 0.00
- cancer · score 0.00
- diabetes mellitus · score 0.00
- chronic kidney disease · score 0.00
- chronic lung disease · score 0.00
- type 1 diabetes mellitus · score 0.00
- COVID-19 · score 0.00
- Renal insufficiency · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UBD0-F1 | alphafold | PREDICTED | 54.99 | — |
Amino-acid sequence (423 residues)
MEDKRSLSMA RCEERNSRGQ DHGLERVPFP PQLQSETYLH PADPSPAWDD PGSTGSPNLR LLTEEIAFQP LAEEASFRRP HPDGDVPPQG EDNLLSLPFP QKLWRLVSSN QFSSIWWDDS GACRVINQKL FEKEILKRDV AHKVFATTSI KSFFRQLNLY GFRKRRQCTF RTFTRIFSAK RLVSILNKLE FYCHPYFQRD SPHLLVRMKR RVGVKSAPRH QEEDKPEAAG SCLAPADTEQ QDHTSPNEND QVTPQHREPA GPNTQIRSGS APPATPVMVP DSAVASDNSP VTQPAGEWSE GSQAHVTPVA AVPGPAALPF LYVPGSPTQM NSYGPVVALP TASRSTLAMD TTGLPAPGML PFCHLWVPVT LVAAGAAQPA ASMVMFPHLP ALHHHCPHSH RTSQYMPASD GPQAYPDYAD QST
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