Cytokine SCM-1 beta (XCL2)

Homo sapiens — UniProt Q9UBD3

Gene: XCL2Homo sapiensSwissProt reviewed

About Cytokine SCM-1 beta

Cytokine SCM-1 beta (XCL2) is a protein from Homo sapiens identified by UniProt accession Q9UBD3, 114 residues long. MolForge cross-references it against 0 known binders and 82 disease associations.

Target properties

Protein nameCytokine SCM-1 beta
UniProt accessionQ9UBD3
GeneXCL2
OrganismHomo sapiens
Length114 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (82)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.39
  • blood protein measurement · score 0.37
  • psoriasis · score 0.28
  • ovarian cancer · score 0.26
  • head and neck squamous cell carcinoma · score 0.16
  • neutrophil count · score 0.11
  • cancer · score 0.08
  • neoplasm · score 0.08
  • PHF-tau measurement · score 0.06
  • lymphoma · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UBD3-F1alphafoldPREDICTED80.70—

Amino-acid sequence (114 residues)

MRLLILALLG ICSLTAYIVE GVGSEVSHRR TCVSLTTQRL PVSRIKTYTI TEGSLRAVIF ITKRGLKVCA DPQATWVRDV VRSMDRKSNT RNNMIQTKPT GTQQSTNTAV TLTG

Explore Cytokine SCM-1 beta with MolForge

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Quick facts

UniProtQ9UBD3
GeneXCL2
OrganismHomo sapiens
Length114
Binders0
Diseases82
View on UniProt