About Cardiotrophin-like cytokine factor 1
Cardiotrophin-like cytokine factor 1 (CLCF1) is a protein
from Homo sapiens identified by UniProt accession
Q9UBD9, 225 residues long.
MolForge cross-references it against 0 known binders and
121 disease associations.
Target properties
| Protein name | Cardiotrophin-like cytokine factor 1 |
| UniProt accession | Q9UBD9 |
| Gene | CLCF1 |
| Organism | Homo sapiens |
| Length | 225 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (121)
Diseases linked to this target (Open Targets).
- cold-induced sweating syndrome · score 0.57
- Crisponi syndrome · score 0.37
- acute lymphoblastic leukemia · score 0.13
- cutaneous melanoma · score 0.10
- breast adenocarcinoma · score 0.09
- hepatocellular carcinoma · score 0.09
- glioblastoma multiforme · score 0.08
- Romano-Ward syndrome · score 0.06
- Osteoporosis · score 0.05
- Familial short QT syndrome · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q9UBD9-F1 | alphafold | PREDICTED | 81.59 | — |
Amino-acid sequence (225 residues)
MDLRAGDSWG MLACLCTVLW HLPAVPALNR TGDPGPGPSI QKTYDLTRYL EHQLRSLAGT YLNYLGPPFN EPDFNPPRLG AETLPRATVD LEVWRSLNDK LRLTQNYEAY SHLLCYLRGL NRQAATAELR RSLAHFCTSL QGLLGSIAGV MAALGYPLPQ PLPGTEPTWT PGPAHSDFLQ KMDDFWLLKE LQTWLWRSAK DFNRLKKKMQ PPAAAVTLHL GAHGF
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