Cardiotrophin-like cytokine factor 1 (CLCF1)

Homo sapiens — UniProt Q9UBD9

Gene: CLCF1Homo sapiensSwissProt reviewed

About Cardiotrophin-like cytokine factor 1

Cardiotrophin-like cytokine factor 1 (CLCF1) is a protein from Homo sapiens identified by UniProt accession Q9UBD9, 225 residues long. MolForge cross-references it against 0 known binders and 121 disease associations.

Target properties

Protein nameCardiotrophin-like cytokine factor 1
UniProt accessionQ9UBD9
GeneCLCF1
OrganismHomo sapiens
Length225 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (121)

Diseases linked to this target (Open Targets).

  • cold-induced sweating syndrome · score 0.57
  • Crisponi syndrome · score 0.37
  • acute lymphoblastic leukemia · score 0.13
  • cutaneous melanoma · score 0.10
  • breast adenocarcinoma · score 0.09
  • hepatocellular carcinoma · score 0.09
  • glioblastoma multiforme · score 0.08
  • Romano-Ward syndrome · score 0.06
  • Osteoporosis · score 0.05
  • Familial short QT syndrome · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UBD9-F1alphafoldPREDICTED81.59—

Amino-acid sequence (225 residues)

MDLRAGDSWG MLACLCTVLW HLPAVPALNR TGDPGPGPSI QKTYDLTRYL EHQLRSLAGT YLNYLGPPFN EPDFNPPRLG AETLPRATVD LEVWRSLNDK LRLTQNYEAY SHLLCYLRGL NRQAATAELR RSLAHFCTSL QGLLGSIAGV MAALGYPLPQ PLPGTEPTWT PGPAHSDFLQ KMDDFWLLKE LQTWLWRSAK DFNRLKKKMQ PPAAAVTLHL GAHGF

Explore Cardiotrophin-like cytokine factor 1 with MolForge

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Quick facts

UniProtQ9UBD9
GeneCLCF1
OrganismHomo sapiens
Length225
Binders0
Diseases121
View on UniProt